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This orthogroup contains 225 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 225 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR21328 | POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| Pfam | PF00644 | PARP — Poly(ADP-ribose) polymerase catalytic domain | 197 / 225 | 87.6% | 98.0% of 201 | ≥80% support |
| GO | GO:0005635 Cellular Component | nuclear envelope | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0019900 Molecular Function | kinase binding | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0030968 Biological Process | endoplasmic reticulum unfolded protein response | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0043539 Molecular Function | protein serine/threonine kinase activator activity | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0071782 Cellular Component | endoplasmic reticulum tubular network | 201 / 225 | 89.3% | 99.5% of 202 | ≥80% support |
| GO | GO:0003950 Molecular Function | NAD+-protein poly-ADP-ribosyltransferase activity | 199 / 225 | 88.4% | 98.5% of 202 | ≥80% support |
| Pfam | PF18084 | ARTD15_N — ARTD15 N-terminal domain | 167 / 225 | 74.2% | 83.1% of 201 | ≥50% support |
| KEGG | K00774 | PARP16 — Enzymes with EC numbers | 167 / 225 | 74.2% | 98.8% of 169 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Leptoseris scabra | ANN00369-RA | CAH3145160.1 | unnamed protein product [Porites lobata] | Q7TMM8 Protein mono-ADP-ribosyltransferase PARP16 OS=Mus musculus O | JBrowse |
