Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 18 (filtered to MAURE · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Madracis auretenraENSIHXP00000003209.1KAJ7327746.1Heart- and neural crest derivatives-expressed protein 2 [Desmophyllum pertusum]P57102
Heart- and neural crest derivatives-expressed protein 2 OS=D
JBrowse
Madracis auretenraENSIHXP00000005385.1XP_027045320.1heart- and neural crest derivatives-expressed protein 2-like [Pocillopora damicornis]P57101
Heart- and neural crest derivatives-expressed protein 2 OS=X
JBrowse
Madracis auretenraENSIHXP00000017074.1KAJ7330201.1Achaete-scute bHLH transcription factor [Desmophyllum pertusum]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Madracis auretenraENSIHXP00000020173.1XP_020629353.1helix-loop-helix protein 2-like [Orbicella faveolata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Madracis auretenraENSIHXP00000020473.1XP_027048909.1achaete-scute homolog 3-like [Pocillopora damicornis]M0QWB7
Achaete-scute homolog 5 OS=Mus musculus OX=10090 GN=Ascl5 PE
JBrowse
Madracis auretenraENSIHXP00000022550.1XP_022786197.1achaete-scute homolog 1-like [Stylophora pistillata]Q06234
Achaete-scute homolog 1 OS=Xenopus laevis OX=8355 GN=ascl1 P
JBrowse
Madracis auretenraENSIHXP00000025194.1XP_027039118.1protein atonal homolog 8-like [Pocillopora damicornis]D2CLZ9
Transcription factor atoh8 OS=Danio rerio OX=7955 GN=atoh8 P
JBrowse
Madracis auretenraENSIHXP00000027705.1XP_027048334.1transcription factor 15-like [Pocillopora damicornis]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Madracis auretenraENSIHXP00000027739.1XP_027048334.1transcription factor 15-like [Pocillopora damicornis]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Madracis auretenraENSIHXP00000028228.1XP_027048338.1neurogenin-3-like [Pocillopora damicornis]Q9Z2E5
Transcription factor Atoh7 OS=Mus musculus OX=10090 GN=Atoh7
JBrowse
Madracis auretenraENSIHXP00000028432.1CAH3147780.1unnamed protein product [Pocillopora meandrina]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Madracis auretenraENSIHXP00000028749.1XP_027048318.1protein atonal homolog 7-A-like [Pocillopora damicornis]–JBrowse
Madracis auretenraENSIHXP00000028837.1XP_020616475.1transcription factor 15-like [Orbicella faveolata]–JBrowse
Madracis auretenraENSIHXP00000029618.1KAJ7391922.1hypothetical protein OS493_016227 [Desmophyllum pertusum]Q923Z4
Fer3-like protein OS=Mus musculus OX=10090 GN=Ferd3l PE=1 SV
JBrowse
Madracis auretenraENSIHXP00000029635.1XP_022804052.1T-cell acute lymphocytic leukemia protein 2-like [Stylophora pistillata]Q96RJ6
Fer3-like protein OS=Homo sapiens OX=9606 GN=FERD3L PE=1 SV=
JBrowse
Madracis auretenraENSIHXP00000033161.1CAH3116808.1unnamed protein product [Pocillopora meandrina]Q90YI8
T-cell acute lymphocytic leukemia protein 1 OS=Takifugu rubr
JBrowse
Madracis auretenraENSIHXP00000033914.1CAH3116812.1unnamed protein product, partial [Pocillopora meandrina]P27792
Protein lyl-1 OS=Mus musculus OX=10090 GN=Lyl1 PE=2 SV=2
JBrowse
Madracis auretenraENSIHXP00000034939.1CAH3116810.1unnamed protein product [Pocillopora meandrina]O93507
T-cell acute lymphocytic leukemia protein 1 homolog OS=Danio
JBrowse
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