Gene Family

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Member genes
5,952
Species
144
Sequences
5,953
Best annotation support
88.7%

1 sequences in this family share a gene identifier with another member, so the 5,953 sequences above are 5,952 distinct genes — none is counted twice.

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 88.7% of the 5,952 members.

Support counts the member genes carrying the term. % of genes is that count over all 5,952 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR18945NEUROTRANSMITTER GATED ION CHANNEL5281 / 5,95288.7%99.5%
of 5,310
≥80% support
PfamPF02931Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain5226 / 5,95287.8%95.8%
of 5,453
≥80% support
PfamPF02932Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region5080 / 5,95285.4%93.2%
of 5,453
≥80% support
GOGO:0016020
Cellular Component
membrane5523 / 5,95292.8%100.0%
of 5,523
≥80% support
GOGO:0006811
Biological Process
monoatomic ion transport5520 / 5,95292.7%100.0%
of 5,523
≥80% support
GOGO:0005216
Molecular Function
monoatomic ion channel activity5302 / 5,95289.1%96.0%
of 5,523
≥80% support
GOGO:0034220
Biological Process
monoatomic ion transmembrane transport5302 / 5,95289.1%96.0%
of 5,523
≥80% support
GOGO:0004888
Molecular Function
transmembrane signaling receptor activity5302 / 5,95289.1%96.0%
of 5,523
≥80% support
GOGO:0005230
Molecular Function
extracellular ligand-gated monoatomic ion channel activity5287 / 5,95288.8%95.7%
of 5,523
≥80% support
GOGO:0005887
Cellular Component
plasma membrane5282 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0042391
Biological Process
regulation of membrane potential5282 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0007268
Biological Process
chemical synaptic transmission5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0007165
Biological Process
signal transduction5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0030594
Molecular Function
neurotransmitter receptor activity5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0043005
Cellular Component
neuron projection5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0045202
Cellular Component
synapse5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0050877
Biological Process
nervous system process5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:1904315
Molecular Function
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0005231
Molecular Function
excitatory extracellular ligand-gated monoatomic ion channel activity5281 / 5,95288.7%95.6%
of 5,523
≥80% support
GOGO:0022848
Molecular Function
acetylcholine-gated monoatomic cation-selective channel activity3030 / 5,95250.9%54.9%
of 5,523
≥50% support
GOGO:0045211
Cellular Component
postsynaptic membrane3021 / 5,95250.8%54.7%
of 5,523
≥50% support
📊 Total members in OG0000057: 66 (filtered to MCACT · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

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