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This orthogroup contains 592 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 592 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11889 | HEDGEHOG | 533 / 592 | 90.0% | 98.0% of 544 | ≥80% support |
| Pfam | PF01079 | Hint | 519 / 592 | 87.7% | 93.9% of 553 | ≥80% support |
| GO | GO:0007267 Biological Process | cell-cell signaling | 535 / 592 | 90.4% | 96.8% of 553 | ≥80% support |
| GO | GO:0016540 Biological Process | protein autoprocessing | 519 / 592 | 87.7% | 93.9% of 553 | ≥80% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 513 / 592 | 86.7% | 92.8% of 553 | ≥80% support |
| GO | GO:0010468 Biological Process | regulation of gene expression | 513 / 592 | 86.7% | 92.8% of 553 | ≥80% support |
| GO | GO:0005615 Cellular Component | extracellular space | 512 / 592 | 86.5% | 92.6% of 553 | ≥80% support |
| GO | GO:0001708 Biological Process | cell fate specification | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0005113 Molecular Function | patched binding | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0005509 Molecular Function | calcium ion binding | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| GO | GO:0007224 Biological Process | smoothened signaling pathway | 511 / 592 | 86.3% | 92.4% of 553 | ≥80% support |
| Pfam | PF01085 | HH_signal — Hedgehog amino-terminal signalling domain | 370 / 592 | 62.5% | 66.9% of 553 | ≥50% support |
| GO | GO:0016539 Biological Process | intein-mediated protein splicing | 389 / 592 | 65.7% | 70.3% of 553 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora cactus | BRAKERNUSP00000003005.1 | XP_015757471.1 | PREDICTED: protein hedgehog-like [Acropora digitifera] | Q91611 Desert hedgehog protein B OS=Xenopus laevis OX=8355 GN=dhh-b | JBrowse |
| Montipora cactus | BRAKERNUSP00000010696.1 | XP_029199743.2 | cadherin-23-like isoform X2 [Acropora millepora] | Q91035 Sonic hedgehog protein OS=Gallus gallus OX=9031 GN=SHH PE=1 | JBrowse |
| Montipora cactus | BRAKERNUSP00000028437.1 | XP_029201585.2 | sonic hedgehog protein-like [Acropora millepora] | Q91035 Sonic hedgehog protein OS=Gallus gallus OX=9031 GN=SHH PE=1 | JBrowse |
| Montipora cactus | BRAKERNUSP00000030120.1 | XP_015756004.1 | PREDICTED: tiggy-winkle hedgehog protein-like [Acropora digitifera] | P79691 Sonic hedgehog protein OS=Carassius auratus OX=7957 GN=shha | JBrowse |
| Montipora cactus | g24612.t1.1 | none | – | JBrowse | |
| Montipora cactus | g35229.t1.1 | none | – | JBrowse | |
| Montipora cactus | g42760.t1.1 | none | – | JBrowse | |
| Montipora cactus | g49449.t1.1 | none | – | JBrowse |
