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This orthogroup contains 376 genes from 95 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 376 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11920 | GUANYLYL CYCLASE | 342 / 376 | 91.0% | 99.7% of 343 | ≥80% support |
| Pfam | PF08376 | NIT | 340 / 376 | 90.4% | 93.7% of 363 | ≥80% support |
| Pfam | PF00211 | Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain | 338 / 376 | 89.9% | 93.1% of 363 | ≥80% support |
| GO | GO:0004383 Molecular Function | guanylate cyclase activity | 343 / 376 | 91.2% | 100.0% of 343 | ≥80% support |
| GO | GO:0006182 Biological Process | cGMP biosynthetic process | 343 / 376 | 91.2% | 100.0% of 343 | ≥80% support |
| GO | GO:0001653 Molecular Function | peptide receptor activity | 342 / 376 | 91.0% | 99.7% of 343 | ≥80% support |
| GO | GO:0004016 Molecular Function | adenylate cyclase activity | 342 / 376 | 91.0% | 99.7% of 343 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 342 / 376 | 91.0% | 99.7% of 343 | ≥80% support |
| GO | GO:0007168 Biological Process | receptor guanylyl cyclase signaling pathway | 342 / 376 | 91.0% | 99.7% of 343 | ≥80% support |
| GO | GO:0009190 Biological Process | cyclic nucleotide biosynthetic process | 340 / 376 | 90.4% | 99.1% of 343 | ≥80% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 340 / 376 | 90.4% | 99.1% of 343 | ≥80% support |
| Pfam | PF07701 | HNOBA — Heme NO binding associated | 293 / 376 | 77.9% | 80.7% of 363 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora cactus | BRAKERNUSP00000014736.1 | XP_015771921.1 | PREDICTED: uncharacterized protein LOC107350213 [Acropora digitifera] | P46197 Atrial natriuretic peptide receptor 2 OS=Bos taurus OX=9913 | JBrowse |
| Montipora cactus | BRAKERNUSP00000054669.1 | XP_029189452.2 | receptor-type guanylate cyclase gcy-22-like isoform X1 [Acropora millepora] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Montipora cactus | g20294.t1.1 | none | – | JBrowse | |
| Montipora cactus | g234.t1.1 | none | – | JBrowse |
