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This orthogroup contains 287 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 287 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10241 | LETHAL 2 GIANT LARVAE PROTEIN | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0019905 Molecular Function | syntaxin binding | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0045159 Molecular Function | myosin II binding | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0050708 Biological Process | regulation of protein secretion | 253 / 287 | 88.2% | 100.0% of 253 | ≥80% support |
| GO | GO:0008593 Biological Process | regulation of Notch signaling pathway | 251 / 287 | 87.5% | 99.2% of 253 | ≥80% support |
| GO | GO:0030864 Cellular Component | cortical actin cytoskeleton | 251 / 287 | 87.5% | 99.2% of 253 | ≥80% support |
| GO | GO:0030866 Biological Process | cortical actin cytoskeleton organization | 251 / 287 | 87.5% | 99.2% of 253 | ≥80% support |
| GO | GO:0032878 Biological Process | regulation of establishment or maintenance of cell polarity | 251 / 287 | 87.5% | 99.2% of 253 | ≥80% support |
| GO | GO:0051294 Biological Process | establishment of spindle orientation | 251 / 287 | 87.5% | 99.2% of 253 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 234 / 287 | 81.5% | 92.5% of 253 | ≥80% support |
| Pfam | PF08366 | LLGL | 225 / 287 | 78.4% | 95.3% of 236 | ≥50% support |
| Pfam | PF08596 | Lgl_C — Lethal giant larvae(Lgl) like, C-terminal | 205 / 287 | 71.4% | 86.9% of 236 | ≥50% support |
| KEGG | K06094 | LLGL — Membrane trafficking | 216 / 287 | 75.3% | 98.6% of 219 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Montipora cactus | BRAKERNUSP00000041697.1 | XP_029191733.2 | LLGL scribble cell polarity complex component 2-like isoform X1 [Acropora millepora] | Q6P1M3 LLGL scribble cell polarity complex component 2 OS=Homo sapi | JBrowse |
| Montipora cactus | BRAKERNUSP00000041698.1 | XP_029191733.2 | LLGL scribble cell polarity complex component 2-like isoform X1 [Acropora millepora] | Q6P1M3 LLGL scribble cell polarity complex component 2 OS=Homo sapi | JBrowse |
| Montipora cactus | g27501.t1.1 | none | – | JBrowse | |
| Montipora cactus | g27501.t2.1 | none | – | JBrowse |
