Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 17 (filtered to MMEAN · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Meandrina meandritesENSVBPP00000017288.1XP_020629881.1heart- and neural crest derivatives-expressed protein 2-like [Orbicella faveolata]Q90690
Heart- and neural crest derivatives-expressed protein 2 OS=G
JBrowse
Meandrina meandritesENSVBPP00000017297.1XP_020629881.1heart- and neural crest derivatives-expressed protein 2-like [Orbicella faveolata]Q90690
Heart- and neural crest derivatives-expressed protein 2 OS=G
JBrowse
Meandrina meandritesENSVBPP00000021567.1KAJ7327746.1Heart- and neural crest derivatives-expressed protein 2 [Desmophyllum pertusum]P57102
Heart- and neural crest derivatives-expressed protein 2 OS=D
JBrowse
Meandrina meandritesENSVBPP00000030941.1RMX55292.1hypothetical protein pdam_00017789 [Pocillopora damicornis]Q96SQ7
Transcription factor ATOH8 OS=Homo sapiens OX=9606 GN=ATOH8
JBrowse
Meandrina meandritesENSVBPP00000030945.1XP_020622947.1protein atonal homolog 8-like [Orbicella faveolata]Q96SQ7
Transcription factor ATOH8 OS=Homo sapiens OX=9606 GN=ATOH8
JBrowse
Meandrina meandritesENSVBPP00000035191.1XP_020617720.1T-cell acute lymphocytic leukemia protein 1 homolog [Orbicella faveolata]P27792
Protein lyl-1 OS=Mus musculus OX=10090 GN=Lyl1 PE=2 SV=2
JBrowse
Meandrina meandritesENSVBPP00000035270.1XP_020629353.1helix-loop-helix protein 2-like [Orbicella faveolata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Meandrina meandritesENSVBPP00000035291.1XP_020629353.1helix-loop-helix protein 2-like [Orbicella faveolata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Meandrina meandritesENSVBPP00000036414.1XP_020617719.1T-cell acute lymphocytic leukemia protein 1-like [Orbicella faveolata]Q16559
T-cell acute lymphocytic leukemia protein 2 OS=Homo sapiens
JBrowse
Meandrina meandritesENSVBPP00000038585.1XP_020616452.1pancreas transcription factor 1 subunit alpha-like [Orbicella faveolata]–JBrowse
Meandrina meandritesENSVBPP00000038593.1XP_020616452.1pancreas transcription factor 1 subunit alpha-like [Orbicella faveolata]–JBrowse
Meandrina meandritesENSVBPP00000038679.1XP_020617680.1T-cell acute lymphocytic leukemia protein 1-like [Orbicella faveolata]P27792
Protein lyl-1 OS=Mus musculus OX=10090 GN=Lyl1 PE=2 SV=2
JBrowse
Meandrina meandritesENSVBPP00000040412.1XP_020616475.1transcription factor 15-like [Orbicella faveolata]–JBrowse
Meandrina meandritesENSVBPP00000040830.1KAJ7391922.1hypothetical protein OS493_016227 [Desmophyllum pertusum]Q923Z4
Fer3-like protein OS=Mus musculus OX=10090 GN=Ferd3l PE=1 SV
JBrowse
Meandrina meandritesENSVBPP00000041599.1XP_020616472.1transcription factor 15-like isoform X1 [Orbicella faveolata]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Meandrina meandritesENSVBPP00000041765.1PFX33236.1Transcription factor 15 [Stylophora pistillata]P59101
Basic helix-loop-helix transcription factor scleraxis OS=Gal
JBrowse
Meandrina meandritesENSVBPP00000042902.1XP_020619260.1pancreas transcription factor 1 subunit alpha-like [Orbicella faveolata]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
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