Gene Family

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Member genes
401
Species
143
Sequences
401
Best annotation support
92.8%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 92.8% of the 401 members.

Support counts the member genes carrying the term. % of genes is that count over all 401 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR46022PROTEIN PATCHED372 / 40192.8%100.0%
of 372
≥80% support
PfamPF02460Patched327 / 40181.6%95.1%
of 344
≥80% support
GOGO:0005886
Cellular Component
plasma membrane372 / 40192.8%100.0%
of 372
≥80% support
GOGO:0005119
Molecular Function
smoothened binding370 / 40192.3%99.5%
of 372
≥80% support
GOGO:0008158
Molecular Function
hedgehog receptor activity370 / 40192.3%99.5%
of 372
≥80% support
GOGO:0045879
Biological Process
negative regulation of smoothened signaling pathway370 / 40192.3%99.5%
of 372
≥80% support
GOGO:0097108
Molecular Function
hedgehog family protein binding370 / 40192.3%99.5%
of 372
≥80% support
GOGO:0016020
Cellular Component
membrane328 / 40181.8%88.2%
of 372
≥80% support
KEGGK06225PTCH1 — Basal cell carcinoma261 / 40165.1%99.6%
of 262
≥50% support
📊 Total members in OG0002058: 11 (filtered to OFAVE · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Orbicella faveolataXP_020624650.1XP_020624650.1protein patched homolog 1-like isoform X1 [Orbicella faveolata]Q90693
Protein patched homolog 1 OS=Gallus gallus OX=9031 GN=PTCH1
JBrowse
Orbicella faveolataXP_020624651.1XP_020624651.1protein patched homolog 1-like isoform X2 [Orbicella faveolata]Q61115
Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1
JBrowse
Orbicella faveolataXP_020624652.1XP_020624652.1protein patched homolog 1-like [Orbicella faveolata]Q61115
Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1
JBrowse
Orbicella faveolataXP_020624674.1XP_020624674.1uncharacterized protein LOC110062153 [Orbicella faveolata]Q98864
Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE
JBrowse
Orbicella faveolataXP_020624703.1XP_020624703.1protein patched homolog 1-like isoform X1 [Orbicella faveolata]Q98864
Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE
JBrowse
Orbicella faveolataXP_020624704.1XP_020624703.1protein patched homolog 1-like isoform X1 [Orbicella faveolata]Q98864
Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE
JBrowse
Orbicella faveolataXP_020624706.1XP_020624706.1protein patched homolog 1-like [Orbicella faveolata]Q61115
Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1
JBrowse
Orbicella faveolataXP_020624707.1XP_020624706.1protein patched homolog 1-like [Orbicella faveolata]Q61115
Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1
JBrowse
Orbicella faveolataXP_020624708.1XP_020624708.1protein patched homolog 1-like isoform X1 [Orbicella faveolata]Q61115
Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1
JBrowse
Orbicella faveolataXP_020624709.1XP_020624709.1protein patched-like isoform X2 [Orbicella faveolata]P18502
Protein patched OS=Drosophila melanogaster OX=7227 GN=ptc PE
JBrowse
Orbicella faveolataXP_020624710.1XP_020624710.1protein patched homolog 1-like isoform X3 [Orbicella faveolata]Q90693
Protein patched homolog 1 OS=Gallus gallus OX=9031 GN=PTCH1
JBrowse
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