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This orthogroup contains 3,972 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,972 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11733 | ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED | 3597 / 3,972 | 90.6% | 99.8% of 3,605 | ≥80% support |
| Pfam | PF05649 | Peptidase_M13_N — Peptidase family M13 | 3359 / 3,972 | 84.6% | 91.9% of 3,656 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 3664 / 3,972 | 92.3% | 100.0% of 3,666 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 3627 / 3,972 | 91.3% | 98.9% of 3,666 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 3598 / 3,972 | 90.6% | 98.2% of 3,666 | ≥80% support |
| GO | GO:0016485 Biological Process | protein processing | 3574 / 3,972 | 90.0% | 97.5% of 3,666 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 3515 / 3,972 | 88.5% | 95.9% of 3,666 | ≥80% support |
| Pfam | PF01431 | Peptidase_M13 — Peptidase family M13 | 3117 / 3,972 | 78.5% | 85.3% of 3,656 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3978301.1 | CAB3978301.1 | endothelin-converting enzyme 1-like [Paramuricea clavata] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Paramuricea clavata | CAB3983457.1 | CAB3983457.1 | endothelin-converting enzyme 2-like isoform X2, partial [Paramuricea clavata] | P0DPD6 Endothelin-converting enzyme 2 OS=Homo sapiens OX=9606 GN=EC | JBrowse |
| Paramuricea clavata | CAB3983458.1 | CAB3983458.1 | endothelin-converting enzyme 2-like isoform X2, partial [Paramuricea clavata] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Paramuricea clavata | CAB3988457.1 | CAB3988457.1 | endothelin-converting enzyme 1-like [Paramuricea clavata] | Q9W436 Neprilysin-1 OS=Drosophila melanogaster OX=7227 GN=Nep1 PE=2 | JBrowse |
| Paramuricea clavata | CAB3988916.1 | CAB3988916.1 | endothelin-converting enzyme homolog, partial [Paramuricea clavata] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Paramuricea clavata | CAB3988922.1 | CAB3988922.1 | endothelin-converting enzyme 2 isoform X2 [Paramuricea clavata] | P0DPD6 Endothelin-converting enzyme 2 OS=Homo sapiens OX=9606 GN=EC | JBrowse |
| Paramuricea clavata | CAB3992483.1 | CAB3992483.1 | endothelin-converting enzyme homolog isoform X1, partial [Paramuricea clavata] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Paramuricea clavata | CAB3992484.1 | CAB3992484.1 | endothelin-converting enzyme homolog isoform X1, partial [Paramuricea clavata] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Paramuricea clavata | CAB3992485.1 | CAB3992485.1 | endothelin-converting enzyme homolog isoform X1, partial [Paramuricea clavata] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Paramuricea clavata | CAB3992486.1 | CAB3992486.1 | endothelin-converting enzyme homolog isoform X1, partial [Paramuricea clavata] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Paramuricea clavata | CAB3992487.1 | CAB3992487.1 | endothelin-converting enzyme homolog isoform X1, partial [Paramuricea clavata] | P42892 Endothelin-converting enzyme 1 OS=Homo sapiens OX=9606 GN=EC | JBrowse |
| Paramuricea clavata | CAB3992501.1 | CAB3992501.1 | endothelin-converting enzyme homolog [Paramuricea clavata] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Paramuricea clavata | CAB3992786.1 | CAB3992786.1 | neprilysin, partial [Paramuricea clavata] | P07861 Neprilysin OS=Rattus norvegicus OX=10116 GN=Mme PE=1 SV=2 | JBrowse |
| Paramuricea clavata | CAB3994614.1 | CAB3994614.1 | endothelin-converting enzyme 1-like [Paramuricea clavata] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Paramuricea clavata | CAB3995189.1 | CAB3995189.1 | endothelin-converting enzyme homolog [Paramuricea clavata] | Q9W5Y0 Neprilysin-3 OS=Drosophila melanogaster OX=7227 GN=Nep3 PE=2 | JBrowse |
| Paramuricea clavata | CAB3996359.1 | CAB3996359.1 | endothelin-converting enzyme 2-like isoform X2 [Paramuricea clavata] | P0C1T0 Membrane metallo-endopeptidase-like 1 OS=Rattus norvegicus O | JBrowse |
| Paramuricea clavata | CAB3996670.1 | CAB3996670.1 | collagen alpha-1(VII) chain-like [Paramuricea clavata] | Q495T6 Membrane metallo-endopeptidase-like 1 OS=Homo sapiens OX=960 | JBrowse |
| Paramuricea clavata | CAB3997560.1 | CAB3997560.1 | neprilysin-2 isoform X1 [Paramuricea clavata] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Paramuricea clavata | CAB3998205.1 | CAB3998205.1 | endothelin-converting enzyme 1-like [Paramuricea clavata] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Paramuricea clavata | CAB3998527.1 | CAB3998527.1 | endothelin-converting enzyme homolog isoform X2, partial [Paramuricea clavata] | Q61391 Neprilysin OS=Mus musculus OX=10090 GN=Mme PE=1 SV=3 | JBrowse |
