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This orthogroup contains 903 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 903 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | 675 / 903 | 74.8% | 91.1% of 741 | ≥50% support |
| Pfam | PF00632 | HECT | 672 / 903 | 74.4% | 85.4% of 787 | ≥50% support |
| Pfam | PF00397 | WW | 639 / 903 | 70.8% | 81.2% of 787 | ≥50% support |
| Pfam | PF00168 | C2 | 579 / 903 | 64.1% | 73.6% of 787 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 705 / 903 | 78.1% | 94.0% of 750 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 677 / 903 | 75.0% | 90.3% of 750 | ≥50% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 676 / 903 | 74.9% | 90.1% of 750 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 675 / 903 | 74.8% | 90.0% of 750 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 674 / 903 | 74.6% | 89.9% of 750 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 646 / 903 | 71.5% | 86.1% of 750 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3992883.1 | CAB3992883.1 | NEDD4-like E3 ubiquitin- ligase WWP1 [Paramuricea clavata] | Q8BZZ3 NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus | JBrowse |
| Paramuricea clavata | CAB4007765.1 | CAB4007765.1 | E3 ubiquitin- ligase NEDD4-like [Paramuricea clavata] | Q5RBF2 E3 ubiquitin-protein ligase NEDD4-like OS=Pongo abelii OX=96 | JBrowse |
| Paramuricea clavata | CAB4008591.1 | CAB4008591.1 | E3 ubiquitin- ligase HECW2-like [Paramuricea clavata] | Q6I6G8 E3 ubiquitin-protein ligase HECW2 OS=Mus musculus OX=10090 G | JBrowse |
| Paramuricea clavata | CAB4015491.1 | CAB4015491.1 | E3 ubiquitin- ligase HECW2-like, partial [Paramuricea clavata] | Q8K4P8 E3 ubiquitin-protein ligase HECW1 OS=Mus musculus OX=10090 G | JBrowse |
| Paramuricea clavata | CAB4015492.1 | CAB4015491.1 | E3 ubiquitin- ligase HECW2-like, partial [Paramuricea clavata] | Q8K4P8 E3 ubiquitin-protein ligase HECW1 OS=Mus musculus OX=10090 G | JBrowse |
| Paramuricea clavata | CAB4016127.1 | CAB4016127.1 | E3 ubiquitin- ligase NEDD4-like [Paramuricea clavata] | P46935 E3 ubiquitin-protein ligase NEDD4 OS=Mus musculus OX=10090 G | JBrowse |
| Paramuricea clavata | CAB4031744.1 | CAB4031744.1 | E3 ubiquitin- ligase NEDD4-like, partial [Paramuricea clavata] | Q8CFI0 E3 ubiquitin-protein ligase NEDD4-like OS=Mus musculus OX=10 | JBrowse |
| Paramuricea clavata | CAB4044032.1 | CAB4044032.1 | E3 ubiquitin- ligase NEDD4-like, partial [Paramuricea clavata] | P46934 E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens OX=9606 GN | JBrowse |
