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This orthogroup contains 654 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 654 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10127 | DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING | 358 / 654 | 54.7% | 73.4% of 488 | ≥50% support |
| Pfam | PF00090 | TSP_1 — Thrombospondin type 1 domain | 426 / 654 | 65.1% | 86.4% of 493 | ≥50% support |
| Pfam | PF01400 | Astacin | 407 / 654 | 62.2% | 82.6% of 493 | ≥50% support |
| Pfam | PF00059 | Lectin_C — Lectin C-type domain | 331 / 654 | 50.6% | 67.1% of 493 | ≥50% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 409 / 654 | 62.5% | 91.3% of 448 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 409 / 654 | 62.5% | 91.3% of 448 | ≥50% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 408 / 654 | 62.4% | 91.1% of 448 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 392 / 654 | 59.9% | 87.5% of 448 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3997791.1 | CAB3997791.1 | Zinc metallo ase nas-6 [Paramuricea clavata] | O43897 Tolloid-like protein 1 OS=Homo sapiens OX=9606 GN=TLL1 PE=1 | JBrowse |
| Paramuricea clavata | CAB3997792.1 | CAB3997792.1 | Zinc metallo ase nas-6 [Paramuricea clavata] | O43897 Tolloid-like protein 1 OS=Homo sapiens OX=9606 GN=TLL1 PE=1 | JBrowse |
| Paramuricea clavata | CAB4021952.1 | CAB4021952.1 | Zinc metallo ase nas-6 [Paramuricea clavata] | O57460 Dorsal-ventral patterning tolloid-like protein 1 OS=Danio re | JBrowse |
| Paramuricea clavata | CAB4021953.1 | CAB4021952.1 | Zinc metallo ase nas-6 [Paramuricea clavata] | O57460 Dorsal-ventral patterning tolloid-like protein 1 OS=Danio re | JBrowse |
| Paramuricea clavata | CAB4021954.1 | CAB4021954.1 | Hypothetical predicted protein [Paramuricea clavata] | Q9WVM6 Tolloid-like protein 2 OS=Mus musculus OX=10090 GN=Tll2 PE=1 | JBrowse |
