← Back to the gene family browser
This orthogroup contains 544 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 544 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10953 | UBIQUITIN-ACTIVATING ENZYME E1 | 482 / 544 | 88.6% | 99.2% of 486 | ≥80% support |
| Pfam | PF00899 | ThiF | 463 / 544 | 85.1% | 93.4% of 496 | ≥80% support |
| GO | GO:0008641 Molecular Function | ubiquitin-like modifier activating enzyme activity | 497 / 544 | 91.4% | 100.0% of 497 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 482 / 544 | 88.6% | 97.0% of 497 | ≥80% support |
| GO | GO:0032446 Biological Process | protein modification by small protein conjugation | 482 / 544 | 88.6% | 97.0% of 497 | ≥80% support |
| Pfam | PF10585 | UBA_E1_SCCH — Ubiquitin-activating enzyme, SCCH domain | 431 / 544 | 79.2% | 86.9% of 496 | ≥50% support |
| Pfam | PF16190 | E1_FCCH — Ubiquitin-activating enzyme E1 FCCH domain | 408 / 544 | 75.0% | 82.3% of 496 | ≥50% support |
| Pfam | PF16191 | E1_4HB — Ubiquitin-activating enzyme E1 four-helix bundle | 392 / 544 | 72.1% | 79.0% of 496 | ≥50% support |
| Pfam | PF09358 | E1_UFD — Ubiquitin fold domain | 374 / 544 | 68.8% | 75.4% of 496 | ≥50% support |
| GO | GO:0004839 Molecular Function | ubiquitin activating enzyme activity | 410 / 544 | 75.4% | 82.5% of 497 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 410 / 544 | 75.4% | 82.5% of 497 | ≥50% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 410 / 544 | 75.4% | 82.5% of 497 | ≥50% support |
| GO | GO:0006974 Biological Process | DNA damage response | 410 / 544 | 75.4% | 82.5% of 497 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 410 / 544 | 75.4% | 82.5% of 497 | ≥50% support |
| GO | GO:0036211 Biological Process | protein modification process | 399 / 544 | 73.4% | 80.3% of 497 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4014503.1 | CAB4014503.1 | ubiquitin-like modifier-activating enzyme 6, partial [Paramuricea clavata] | Q8C7R4 Ubiquitin-like modifier-activating enzyme 6 OS=Mus musculus | JBrowse |
| Paramuricea clavata | CAB4016231.1 | CAB4016231.1 | ubiquitin-like modifier-activating enzyme 1 [Paramuricea clavata] | Q29504 Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus c | JBrowse |
| Paramuricea clavata | CAB4019006.1 | CAB4019006.1 | ubiquitin-like modifier-activating enzyme 6, partial [Paramuricea clavata] | A0AVT1 Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens | JBrowse |
| Paramuricea clavata | CAB4019007.1 | CAB4019007.1 | ubiquitin-like modifier-activating enzyme 6, partial [Paramuricea clavata] | A0AVT1 Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens | JBrowse |
| Paramuricea clavata | CAB4023683.1 | CAB4023683.1 | ubiquitin-like modifier-activating enzyme 1, partial [Paramuricea clavata] | Q29504 Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus c | JBrowse |
| Paramuricea clavata | CAB4023684.1 | CAB4023684.1 | ubiquitin-like modifier-activating enzyme 1, partial [Paramuricea clavata] | Q29504 Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus c | JBrowse |
