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This orthogroup contains 475 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 475 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11347 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | 383 / 475 | 80.6% | 98.0% of 391 | ≥80% support |
| Pfam | PF00233 | PDEase_I — 3'5'-cyclic nucleotide phosphodiesterase | 384 / 475 | 80.8% | 96.7% of 397 | ≥80% support |
| GO | GO:0004114 Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | 388 / 475 | 81.7% | 100.0% of 388 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 388 / 475 | 81.7% | 100.0% of 388 | ≥80% support |
| GO | GO:0004115 Molecular Function | 3',5'-cyclic-AMP phosphodiesterase activity | 383 / 475 | 80.6% | 98.7% of 388 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 383 / 475 | 80.6% | 98.7% of 388 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 383 / 475 | 80.6% | 98.7% of 388 | ≥80% support |
| GO | GO:0048471 Cellular Component | perinuclear region of cytoplasm | 383 / 475 | 80.6% | 98.7% of 388 | ≥80% support |
| Pfam | PF18100 | PDE4_UCR — Phosphodiesterase 4 upstream conserved regions (UCR) | 354 / 475 | 74.5% | 89.2% of 397 | ≥50% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 363 / 475 | 76.4% | 93.6% of 388 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3987038.1 | CAB3987038.1 | cAMP-specific 3, 5 -cyclic phosphodiesterase 4C-like isoform X3 [Paramuricea clavata] | Q07343 3',5'-cyclic-AMP phosphodiesterase 4B OS=Homo sapiens OX=960 | JBrowse |