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This orthogroup contains 421 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 421 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19981 | TALIN | 347 / 421 | 82.4% | 99.1% of 350 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 347 / 421 | 82.4% | 98.9% of 351 | ≥80% support |
| GO | GO:0098609 Biological Process | cell-cell adhesion | 347 / 421 | 82.4% | 98.9% of 351 | ≥80% support |
| GO | GO:0005178 Molecular Function | integrin binding | 342 / 421 | 81.2% | 97.4% of 351 | ≥80% support |
| GO | GO:0005925 Cellular Component | focal adhesion | 342 / 421 | 81.2% | 97.4% of 351 | ≥80% support |
| Pfam | PF01608 | I_LWEQ — I/LWEQ domain | 240 / 421 | 57.0% | 71.0% of 338 | ≥50% support |
| Pfam | PF21692 | Talin_R4 — Talin, R4 domain | 235 / 421 | 55.8% | 69.5% of 338 | ≥50% support |
| Pfam | PF00373 | FERM_M — FERM central domain | 235 / 421 | 55.8% | 69.5% of 338 | ≥50% support |
| Pfam | PF09141 | Talin_middle — Talin, middle domain | 234 / 421 | 55.6% | 69.2% of 338 | ≥50% support |
| Pfam | PF08913 | VBS — Vinculin Binding Site | 224 / 421 | 53.2% | 66.3% of 338 | ≥50% support |
| GO | GO:0003779 Molecular Function | actin binding | 285 / 421 | 67.7% | 81.2% of 351 | ≥50% support |
| GO | GO:0051015 Molecular Function | actin filament binding | 257 / 421 | 61.1% | 73.2% of 351 | ≥50% support |
| GO | GO:0007155 Biological Process | cell adhesion | 257 / 421 | 61.1% | 73.2% of 351 | ≥50% support |
| GO | GO:0005856 Cellular Component | cytoskeleton | 246 / 421 | 58.4% | 70.1% of 351 | ≥50% support |
| GO | GO:0005200 Molecular Function | structural constituent of cytoskeleton | 234 / 421 | 55.6% | 66.7% of 351 | ≥50% support |
| GO | GO:0001726 Cellular Component | ruffle | 234 / 421 | 55.6% | 66.7% of 351 | ≥50% support |
| KEGG | K06271 | TLN — Exosome | 211 / 421 | 50.1% | 96.8% of 218 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3994709.1 | CAB3994709.1 | talin-2-like [Paramuricea clavata] | A0A3G2LGI8 Talin OS=Oscarella pearsei OX=1940113 GN=TLN PE=1 SV=1 | JBrowse |
| Paramuricea clavata | CAB4010732.1 | CAB4010732.1 | talin-1-like isoform X1, partial [Paramuricea clavata] | P54939 Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2 | JBrowse |
| Paramuricea clavata | CAB4010733.1 | CAB4010733.1 | talin-1-like isoform X1, partial [Paramuricea clavata] | P54939 Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2 | JBrowse |
| Paramuricea clavata | CAB4010734.1 | CAB4010734.1 | talin-1-like isoform X1, partial [Paramuricea clavata] | A0A3G2LGI8 Talin OS=Oscarella pearsei OX=1940113 GN=TLN PE=1 SV=1 | JBrowse |
| Paramuricea clavata | CAB4020424.1 | CAB4020424.1 | talin-1 isoform X3, partial [Paramuricea clavata] | Q71LX4 Talin-2 OS=Mus musculus OX=10090 GN=Tln2 PE=1 SV=3 | JBrowse |