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This orthogroup contains 362 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 362 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12287 | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN | 304 / 362 | 84.0% | 99.4% of 306 | ≥80% support |
| GO | GO:0003779 Molecular Function | actin binding | 304 / 362 | 84.0% | 99.0% of 307 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 304 / 362 | 84.0% | 99.0% of 307 | ≥80% support |
| GO | GO:0007266 Biological Process | Rho protein signal transduction | 304 / 362 | 84.0% | 99.0% of 307 | ≥80% support |
| GO | GO:0035023 Biological Process | regulation of Rho protein signal transduction | 304 / 362 | 84.0% | 99.0% of 307 | ≥80% support |
| Pfam | PF08416 | PTB — Phosphotyrosine-binding domain | 225 / 362 | 62.2% | 78.4% of 287 | ≥50% support |
| Pfam | PF18016 | SAM_3 — SAM domain (Sterile alpha motif) | 221 / 362 | 61.1% | 77.0% of 287 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 198 / 362 | 54.7% | 69.0% of 287 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 281 / 362 | 77.6% | 91.5% of 307 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4009607.1 | CAB4009607.1 | Hypothetical predicted protein, partial [Paramuricea clavata] | – | JBrowse |
| Paramuricea clavata | CAB4009608.1 | CAB4009608.1 | Hypothetical predicted protein, partial [Paramuricea clavata] | – | JBrowse |
| Paramuricea clavata | CAB4023712.1 | CAB4023712.1 | Epidermal growth factor receptor kinase substrate 8, partial [Paramuricea clavata] | Q5R4H4 Epidermal growth factor receptor kinase substrate 8 OS=Pongo | JBrowse |
| Paramuricea clavata | CAB4023713.1 | CAB4023713.1 | Epidermal growth factor receptor kinase substrate 8, partial [Paramuricea clavata] | Q5R4H4 Epidermal growth factor receptor kinase substrate 8 OS=Pongo | JBrowse |
| Paramuricea clavata | CAB4023714.1 | CAB4023712.1 | Epidermal growth factor receptor kinase substrate 8, partial [Paramuricea clavata] | Q5R4H4 Epidermal growth factor receptor kinase substrate 8 OS=Pongo | JBrowse |
| Paramuricea clavata | CAB4024900.1 | CAB4024900.1 | epidermal growth factor receptor kinase substrate 8 isoform X1 [Paramuricea clavata] | Q12929 Epidermal growth factor receptor kinase substrate 8 OS=Homo | JBrowse |
| Paramuricea clavata | CAB4024901.1 | CAB4024901.1 | epidermal growth factor receptor kinase substrate 8-like [Paramuricea clavata] | Q12929 Epidermal growth factor receptor kinase substrate 8 OS=Homo | JBrowse |
| Paramuricea clavata | CAB4024902.1 | CAB4024902.1 | epidermal growth factor receptor kinase substrate 8-like [Paramuricea clavata] | P05772 Protein kinase C beta type OS=Oryctolagus cuniculus OX=9986 | JBrowse |
