← Back to the gene family browser
This orthogroup contains 362 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 362 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10169 | DNA TOPOISOMERASE/GYRASE | 318 / 362 | 87.9% | 99.1% of 321 | ≥80% support |
| GO | GO:0000712 Biological Process | resolution of meiotic recombination intermediates | 318 / 362 | 87.9% | 98.2% of 324 | ≥80% support |
| GO | GO:0000819 Biological Process | sister chromatid segregation | 318 / 362 | 87.9% | 98.2% of 324 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 318 / 362 | 87.9% | 98.2% of 324 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 303 / 362 | 83.7% | 93.5% of 324 | ≥80% support |
| GO | GO:0003918 Molecular Function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity | 303 / 362 | 83.7% | 93.5% of 324 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 303 / 362 | 83.7% | 93.5% of 324 | ≥80% support |
| GO | GO:0006265 Biological Process | DNA topological change | 292 / 362 | 80.7% | 90.1% of 324 | ≥80% support |
| Pfam | PF00521 | DNA_topoisoIV — DNA gyrase/topoisomerase IV, subunit A | 263 / 362 | 72.7% | 90.4% of 291 | ≥50% support |
| Pfam | PF16898 | TOPRIM_C — C-terminal associated domain of TOPRIM | 248 / 362 | 68.5% | 85.2% of 291 | ≥50% support |
| Pfam | PF00204 | DNA_gyraseB — DNA gyrase B | 241 / 362 | 66.6% | 82.8% of 291 | ≥50% support |
| Pfam | PF01751 | Toprim | 239 / 362 | 66.0% | 82.1% of 291 | ≥50% support |
| Pfam | PF02518 | HATPase_c — Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | 227 / 362 | 62.7% | 78.0% of 291 | ≥50% support |
| GO | GO:0006259 Biological Process | DNA metabolic process | 259 / 362 | 71.6% | 79.9% of 324 | ≥50% support |
| KEGG | K03164 | TOP2 — Chromosome and associated proteins | 212 / 362 | 58.6% | 96.8% of 219 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3982936.1 | CAB3982936.1 | DNA topoisomerase 2-beta isoform X2 [Paramuricea clavata] | O42131 DNA topoisomerase 2-beta OS=Gallus gallus OX=9031 GN=TOP2B P | JBrowse |
