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This orthogroup contains 287 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 287 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005515 Molecular Function | protein binding | 237 / 287 | 82.6% | 94.1% of 252 | ≥80% support |
| PANTHER | PTHR15090 | SEQUESTOSOME 1-RELATED | 208 / 287 | 72.5% | 99.1% of 210 | ≥50% support |
| Pfam | PF00564 | PB1 | 216 / 287 | 75.3% | 88.2% of 245 | ≥50% support |
| Pfam | PF00569 | ZZ | 184 / 287 | 64.1% | 75.1% of 245 | ≥50% support |
| Pfam | PF16577 | UBA_5 — UBA domain | 165 / 287 | 57.5% | 67.4% of 245 | ≥50% support |
| GO | GO:0000423 Biological Process | mitophagy | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0005080 Molecular Function | protein kinase C binding | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0007032 Biological Process | endosome organization | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0016235 Cellular Component | aggresome | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0035973 Biological Process | aggrephagy | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0044753 Cellular Component | amphisome | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0070530 Molecular Function | K63-linked polyubiquitin modification-dependent protein binding | 208 / 287 | 72.5% | 82.5% of 252 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 188 / 287 | 65.5% | 74.6% of 252 | ≥50% support |
| KEGG | K14381 | SQSTM1 — Exosome | 167 / 287 | 58.2% | 99.4% of 168 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3996786.1 | CAB3996786.1 | sequestosome-1 isoform X2 [Paramuricea clavata] | O08623 Sequestosome-1 OS=Rattus norvegicus OX=10116 GN=Sqstm1 PE=1 | JBrowse |
