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This orthogroup contains 270 genes from 135 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 270 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12991 | NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 | 235 / 270 | 87.0% | 99.6% of 236 | ≥80% support |
| Pfam | PF06218 | NPR2 — Nitrogen permease regulator 2 | 236 / 270 | 87.4% | 100.0% of 236 | ≥80% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| GO | GO:0005774 Cellular Component | vacuolar membrane | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| GO | GO:0010508 Biological Process | positive regulation of autophagy | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| GO | GO:0034198 Biological Process | cellular response to amino acid starvation | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| GO | GO:1904262 Biological Process | negative regulation of TORC1 signaling | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| GO | GO:1990130 Cellular Component | GATOR1 complex | 235 / 270 | 87.0% | 100.0% of 235 | ≥80% support |
| KEGG | K20405 | NPRL2, NPR2 — Membrane trafficking | 145 / 270 | 53.7% | 98.0% of 148 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3990890.1 | CAB3990890.1 | nitrogen permease regulator 2 isoform X2 [Paramuricea clavata] | Q9WUE4 GATOR1 complex protein NPRL2 OS=Mus musculus OX=10090 GN=Npr | JBrowse |
