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🧬 OG0004376

This orthogroup contains 259 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 86.5%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 259 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR15136STROMAL INTERACTION MOLECULE HOMOLOG224 / 25986.5%100.0%
of 224
≥80% support
PfamPF16533SOAR — STIM1 Orai1-activating region209 / 25980.7%94.1%
of 222
≥80% support
GOGO:0002115
Biological Process
store-operated calcium entry224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0005246
Molecular Function
calcium channel regulator activity224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0005509
Molecular Function
calcium ion binding224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0005783
Cellular Component
endoplasmic reticulum224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0005886
Cellular Component
plasma membrane224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0006874
Biological Process
intracellular calcium ion homeostasis224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0032237
Biological Process
activation of store-operated calcium channel activity224 / 25986.5%100.0%
of 224
≥80% support
GOGO:0005515
Molecular Function
protein binding198 / 25976.5%88.4%
of 224
≥50% support
KEGGK16059STIM1 — Transporters168 / 25964.9%98.3%
of 171
≥50% support
📊 Total members in OG0004376: 1 (filtered to PCLAV · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Paramuricea clavataCAB3993462.1CAB3993462.1stromal interaction molecule 1-like isoform X2 [Paramuricea clavata]P83093
Stromal interaction molecule 2 OS=Mus musculus OX=10090 GN=S
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