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This orthogroup contains 244 genes from 125 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 244 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23407 | ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE | 218 / 244 | 89.3% | 100.0% of 218 | ≥80% support |
| Pfam | PF01812 | 5-FTHF_cyc-lig — 5-formyltetrahydrofolate cyclo-ligase family | 217 / 244 | 88.9% | 100.0% of 217 | ≥80% support |
| GO | GO:0009396 Biological Process | folic acid-containing compound biosynthetic process | 218 / 244 | 89.3% | 100.0% of 218 | ≥80% support |
| GO | GO:0030272 Molecular Function | 5-formyltetrahydrofolate cyclo-ligase activity | 218 / 244 | 89.3% | 100.0% of 218 | ≥80% support |
| GO | GO:0035999 Biological Process | tetrahydrofolate interconversion | 218 / 244 | 89.3% | 100.0% of 218 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 210 / 244 | 86.1% | 96.3% of 218 | ≥80% support |
| KEGG | K01934 | MTHFS — One carbon pool by folate | 178 / 244 | 73.0% | 98.9% of 180 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4042697.1 | CAB4042697.1 | 5-formyltetrahydrofolate cyclo-ligase-like [Paramuricea clavata] | Q9D110 5-formyltetrahydrofolate cyclo-ligase OS=Mus musculus OX=100 | JBrowse |
