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This orthogroup contains 242 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 242 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF03165 | MH1 | 196 / 242 | 81.0% | 91.6% of 214 | ≥80% support |
| GO | GO:0005667 Cellular Component | transcription regulator complex | 197 / 242 | 81.4% | 95.2% of 207 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 197 / 242 | 81.4% | 95.2% of 207 | ≥80% support |
| PANTHER | PTHR13703 | SMAD | 182 / 242 | 75.2% | 86.3% of 211 | ≥50% support |
| Pfam | PF00628 | PHD | 159 / 242 | 65.7% | 74.3% of 214 | ≥50% support |
| Pfam | PF13771 | zf-HC5HC2H — PHD-like zinc-binding domain | 131 / 242 | 54.1% | 61.2% of 214 | ≥50% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0007179 Biological Process | transforming growth factor beta receptor signaling pathway | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0009653 Biological Process | anatomical structure morphogenesis | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0030154 Biological Process | cell differentiation | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0030509 Biological Process | BMP signaling pathway | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0060395 Biological Process | SMAD protein signal transduction | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0070411 Molecular Function | I-SMAD binding | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
| GO | GO:0071144 Cellular Component | heteromeric SMAD protein complex | 182 / 242 | 75.2% | 87.9% of 207 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4003842.1 | CAB4003842.1 | mothers against decapentaplegic homolog 4-like [Paramuricea clavata] | P97471 Mothers against decapentaplegic homolog 4 OS=Mus musculus OX | JBrowse |
| Paramuricea clavata | CAB4023208.1 | CAB4023208.1 | histone-lysine N-methyltransferase 2C-like isoform X1 [Paramuricea clavata] | – | JBrowse |
