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This orthogroup contains 239 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 239 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF10174 | Cast — RIM-binding protein of the cytomatrix active zone | 205 / 239 | 85.8% | 98.6% of 208 | ≥80% support |
| PANTHER | PTHR18861 | ELKS/RAB6-INTERACTING/CAST PROTEIN | 173 / 239 | 72.4% | 92.5% of 187 | ≥50% support |
| GO | GO:0007274 Biological Process | neuromuscular synaptic transmission | 173 / 239 | 72.4% | 96.7% of 179 | ≥50% support |
| GO | GO:0048167 Biological Process | regulation of synaptic plasticity | 173 / 239 | 72.4% | 96.7% of 179 | ≥50% support |
| GO | GO:0048788 Cellular Component | cytoskeleton of presynaptic active zone | 173 / 239 | 72.4% | 96.7% of 179 | ≥50% support |
| GO | GO:0048790 Biological Process | maintenance of presynaptic active zone structure | 173 / 239 | 72.4% | 96.7% of 179 | ≥50% support |
| GO | GO:0098882 Molecular Function | structural constituent of presynaptic active zone | 173 / 239 | 72.4% | 96.7% of 179 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4020740.1 | CAB4020740.1 | ELKS Rab6-interacting CAST family member 1-like [Paramuricea clavata] | Q811U3 ELKS/Rab6-interacting/CAST family member 1 OS=Rattus norvegi | JBrowse |
| Paramuricea clavata | CAB4022120.1 | CAB4022120.1 | ELKS Rab6-interacting CAST family member 1-like [Paramuricea clavata] | Q8K3M6 ERC protein 2 OS=Rattus norvegicus OX=10116 GN=Erc2 PE=1 SV= | JBrowse |
| Paramuricea clavata | CAB4027088.1 | CAB4027088.1 | ELKS Rab6-interacting CAST family member 1-like [Paramuricea clavata] | Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens O | JBrowse |
