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This orthogroup contains 232 genes from 132 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 232 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12358 | SPHINGOSINE KINASE | 190 / 232 | 81.9% | 100.0% of 190 | ≥80% support |
| Pfam | PF00781 | DAGK_cat — Diacylglycerol kinase catalytic domain | 189 / 232 | 81.5% | 94.5% of 200 | ≥80% support |
| GO | GO:0016301 Molecular Function | kinase activity | 191 / 232 | 82.3% | 99.0% of 193 | ≥80% support |
| GO | GO:0001729 Molecular Function | ceramide kinase activity | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0047620 Molecular Function | acylglycerol kinase activity | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0046513 Biological Process | ceramide biosynthetic process | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0046512 Biological Process | sphingosine biosynthetic process | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0043231 Cellular Component | intracellular membrane-bounded organelle | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0017050 Molecular Function | D-erythro-sphingosine kinase activity | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0016310 Biological Process | phosphorylation | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0006665 Biological Process | sphingolipid metabolic process | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0004143 Molecular Function | ATP-dependent diacylglycerol kinase activity | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| GO | GO:0001727 Molecular Function | lipid kinase activity | 190 / 232 | 81.9% | 98.5% of 193 | ≥80% support |
| Pfam | PF19712 | AGK_C — Acylglycerol kinase C-terminal | 174 / 232 | 75.0% | 87.0% of 200 | ≥50% support |
| KEGG | K09881 | AGK — Glycerolipid metabolism | 159 / 232 | 68.5% | 98.8% of 161 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4000800.1 | CAB4000800.1 | Acylglycerol kinase, mitochondrial [Paramuricea clavata] | Q9ESW4 Acylglycerol kinase, mitochondrial OS=Mus musculus OX=10090 | JBrowse |