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This orthogroup contains 222 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 222 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10694 | LYSINE-SPECIFIC DEMETHYLASE | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| Pfam | PF02373 | JmjC | 183 / 222 | 82.4% | 97.9% of 187 | ≥80% support |
| GO | GO:0000785 Cellular Component | chromatin | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| GO | GO:0006338 Biological Process | chromatin remodeling | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| GO | GO:0010468 Biological Process | regulation of gene expression | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| GO | GO:0032452 Molecular Function | histone demethylase activity | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| GO | GO:0032454 Molecular Function | histone H3K9 demethylase activity | 183 / 222 | 82.4% | 98.4% of 186 | ≥80% support |
| Pfam | PF02375 | JmjN | 171 / 222 | 77.0% | 91.4% of 187 | ≥50% support |
| Pfam | PF13832 | zf-HC5HC2H_2 — PHD-zinc-finger like domain | 151 / 222 | 68.0% | 80.8% of 187 | ≥50% support |
| Pfam | PF18104 | Tudor_2 — Jumonji domain-containing protein 2A Tudor domain | 142 / 222 | 64.0% | 75.9% of 187 | ≥50% support |
| Pfam | PF13831 | PHD_2 — PHD-finger | 130 / 222 | 58.6% | 69.5% of 187 | ≥50% support |
| KEGG | K06709 | KDM4, JMJD2, JHDM3 — Chromosome and associated proteins | 121 / 222 | 54.5% | 98.4% of 123 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB4013789.1 | CAB4013789.1 | lysine-specific demethylase 4B-like, partial [Paramuricea clavata] | Q8VCD7 Lysine-specific demethylase 4C OS=Mus musculus OX=10090 GN=K | JBrowse |
