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This orthogroup contains 218 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 218 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16160 | FERMITIN 2-RELATED | 190 / 218 | 87.2% | 98.5% of 193 | ≥80% support |
| GO | GO:0005178 Molecular Function | integrin binding | 190 / 218 | 87.2% | 98.5% of 193 | ≥80% support |
| GO | GO:0007160 Biological Process | cell-matrix adhesion | 190 / 218 | 87.2% | 98.5% of 193 | ≥80% support |
| GO | GO:0007229 Biological Process | integrin-mediated signaling pathway | 190 / 218 | 87.2% | 98.5% of 193 | ≥80% support |
| GO | GO:0030055 Cellular Component | cell-substrate junction | 190 / 218 | 87.2% | 98.5% of 193 | ≥80% support |
| Pfam | PF00373 | FERM_M — FERM central domain | 169 / 218 | 77.5% | 90.4% of 187 | ≥50% support |
| Pfam | PF18124 | Kindlin_2_N — Kindlin-2 N-terminal domain | 163 / 218 | 74.8% | 87.2% of 187 | ≥50% support |
| Pfam | PF00169 | PH | 154 / 218 | 70.6% | 82.4% of 187 | ≥50% support |
| KEGG | K17083 | FERMT2, KIND2 — Domain-containing proteins not elsewhere classified | 148 / 218 | 67.9% | 98.0% of 151 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3992369.1 | CAB3992369.1 | fermitin family homolog 2-like [Paramuricea clavata] | Q8CIB5 Fermitin family homolog 2 OS=Mus musculus OX=10090 GN=Fermt2 | JBrowse |
