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This orthogroup contains 213 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 213 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16461 | TOLL-INTERACTING PROTEIN | 191 / 213 | 89.7% | 100.0% of 191 | ≥80% support |
| Pfam | PF02845 | CUE | 181 / 213 | 85.0% | 94.8% of 191 | ≥80% support |
| Pfam | PF00168 | C2 | 176 / 213 | 82.6% | 92.2% of 191 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 191 / 213 | 89.7% | 100.0% of 191 | ≥80% support |
| GO | GO:0006511 Biological Process | ubiquitin-dependent protein catabolic process | 191 / 213 | 89.7% | 100.0% of 191 | ≥80% support |
| GO | GO:0031624 Molecular Function | ubiquitin conjugating enzyme binding | 191 / 213 | 89.7% | 100.0% of 191 | ≥80% support |
| GO | GO:0043130 Molecular Function | ubiquitin binding | 191 / 213 | 89.7% | 100.0% of 191 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 182 / 213 | 85.5% | 95.3% of 191 | ≥80% support |
| KEGG | K05402 | TOLLIP — Exosome | 167 / 213 | 78.4% | 99.4% of 168 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paramuricea clavata | CAB3989123.1 | CAB3989123.1 | toll-interacting isoform X2 [Paramuricea clavata] | Q6INE3 Toll-interacting protein B OS=Xenopus laevis OX=8355 GN=toll | JBrowse |
| Paramuricea clavata | CAB3989124.1 | CAB3989124.1 | toll-interacting isoform X2 [Paramuricea clavata] | Q6INE3 Toll-interacting protein B OS=Xenopus laevis OX=8355 GN=toll | JBrowse |