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This orthogroup contains 1,293 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,293 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10985 | BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED | 1155 / 1,293 | 89.3% | 99.9% of 1,156 | ≥80% support |
| Pfam | PF00010 | HLH — Helix-loop-helix DNA-binding domain | 1131 / 1,293 | 87.5% | 97.1% of 1,165 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 1156 / 1,293 | 89.4% | 98.1% of 1,179 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 1155 / 1,293 | 89.3% | 98.0% of 1,179 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 1155 / 1,293 | 89.3% | 98.0% of 1,179 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 1155 / 1,293 | 89.3% | 98.0% of 1,179 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 1154 / 1,293 | 89.3% | 97.9% of 1,179 | ≥80% support |
| GO | GO:0009952 Biological Process | anterior/posterior pattern specification | 1150 / 1,293 | 88.9% | 97.5% of 1,179 | ≥80% support |
| GO | GO:0050767 Biological Process | regulation of neurogenesis | 1150 / 1,293 | 88.9% | 97.5% of 1,179 | ≥80% support |
| Pfam | PF07527 | Hairy_orange — Hairy Orange | 678 / 1,293 | 52.4% | 58.2% of 1,165 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 716 / 1,293 | 55.4% | 60.7% of 1,179 | ≥50% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 715 / 1,293 | 55.3% | 60.6% of 1,179 | ≥50% support |
| KEGG | K06054 | HES1 — DNA repair and recombination proteins | 756 / 1,293 | 58.5% | 97.2% of 778 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G171150 | CAB3988379.1 | transcription factor HES-1-like [Paramuricea clavata] | Q04666 Transcription factor HES-1 OS=Rattus norvegicus OX=10116 GN= | JBrowse |
| Paragorgia papillata | Ppa0G396630 | XP_028394020.1 | transcription factor HES-4-B-like isoform X2 [Dendronephthya gigantea] | Q90VV1 Transcription factor HES-4-B OS=Xenopus laevis OX=8355 GN=he | JBrowse |
