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This orthogroup contains 896 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 896 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11905 | ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN | 696 / 896 | 77.7% | 99.4% of 700 | ≥50% support |
| Pfam | PF01421 | Reprolysin | 530 / 896 | 59.2% | 79.3% of 668 | ≥50% support |
| Pfam | PF00200 | Disintegrin | 527 / 896 | 58.8% | 78.9% of 668 | ≥50% support |
| Pfam | PF08516 | ADAM_CR — ADAM cysteine-rich | 495 / 896 | 55.3% | 74.1% of 668 | ≥50% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 536 / 896 | 59.8% | 93.2% of 575 | ≥50% support |
| GO | GO:0006508 Biological Process | proteolysis | 534 / 896 | 59.6% | 92.9% of 575 | ≥50% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 530 / 896 | 59.2% | 92.2% of 575 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G034710 | XP_028391203.1 | zinc metalloproteinase-disintegrin-like jararhagin [Dendronephthya gigantea] | Q9H013 Disintegrin and metalloproteinase domain-containing protein | JBrowse |
| Paragorgia papillata | Ppa0G034750 | CAB3991850.1 | Disintegrin and metallo ase domain-containing 12 [Paramuricea clavata] | O43184 Disintegrin and metalloproteinase domain-containing protein | JBrowse |
| Paragorgia papillata | Ppa0G273050 | CAB3979060.1 | disintegrin and metallo ase domain-containing 12-like [Paramuricea clavata] | Q9H013 Disintegrin and metalloproteinase domain-containing protein | JBrowse |
| Paragorgia papillata | Ppa0G308900 | CAB3994597.1 | disintegrin and metallo ase domain-containing 12-like, partial [Paramuricea clavata] | Q61824 Disintegrin and metalloproteinase domain-containing protein | JBrowse |
