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This orthogroup contains 749 genes from 111 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 749 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18966 | IONOTROPIC GLUTAMATE RECEPTOR | 555 / 749 | 74.1% | 90.4% of 614 | ≥50% support |
| Pfam | PF01094 | ANF_receptor — Receptor family ligand binding region | 552 / 749 | 73.7% | 88.8% of 622 | ≥50% support |
| Pfam | PF10613 | Lig_chan-Glu_bd — Ligated ion channel L-glutamate- and glycine-binding site | 522 / 749 | 69.7% | 83.9% of 622 | ≥50% support |
| Pfam | PF00060 | Lig_chan — Ligand-gated ion channel | 513 / 749 | 68.5% | 82.5% of 622 | ≥50% support |
| GO | GO:0015276 Molecular Function | ligand-gated monoatomic ion channel activity | 565 / 749 | 75.4% | 93.7% of 603 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 562 / 749 | 75.0% | 93.2% of 603 | ≥50% support |
| GO | GO:0038023 Molecular Function | signaling receptor activity | 557 / 749 | 74.4% | 92.4% of 603 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 555 / 749 | 74.1% | 92.0% of 603 | ≥50% support |
| GO | GO:0008066 Molecular Function | glutamate receptor activity | 542 / 749 | 72.4% | 89.9% of 603 | ≥50% support |
| GO | GO:0035249 Biological Process | synaptic transmission, glutamatergic | 542 / 749 | 72.4% | 89.9% of 603 | ≥50% support |
| GO | GO:0050804 Biological Process | modulation of chemical synaptic transmission | 542 / 749 | 72.4% | 89.9% of 603 | ≥50% support |
| GO | GO:0098839 Cellular Component | postsynaptic density membrane | 542 / 749 | 72.4% | 89.9% of 603 | ≥50% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 542 / 749 | 72.4% | 89.9% of 603 | ≥50% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 411 / 749 | 54.9% | 68.2% of 603 | ≥50% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 411 / 749 | 54.9% | 68.2% of 603 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G139800 | XP_028411021.1 | glutamate receptor ionotropic, kainate 2-like isoform X1 [Dendronephthya gigantea] | Q91755 Glutamate receptor ionotropic, kainate 2 OS=Xenopus laevis O | JBrowse |
| Paragorgia papillata | Ppa0G139810 | XP_028410929.1 | glutamate receptor 2-like [Dendronephthya gigantea] | A0A2R8QF68 Glutamate receptor ionotropic, kainate 2 OS=Danio rerio OX=7 | JBrowse |
