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This orthogroup contains 618 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 618 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12365 | SPROUTY | 549 / 618 | 88.8% | 99.6% of 551 | ≥80% support |
| Pfam | PF05210 | Sprouty | 560 / 618 | 90.6% | 99.8% of 561 | ≥80% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 560 / 618 | 90.6% | 99.8% of 561 | ≥80% support |
| GO | GO:0009966 Biological Process | regulation of signal transduction | 560 / 618 | 90.6% | 99.8% of 561 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 560 / 618 | 90.6% | 99.8% of 561 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 549 / 618 | 88.8% | 97.9% of 561 | ≥80% support |
| GO | GO:0040037 Biological Process | negative regulation of fibroblast growth factor receptor signaling pathway | 549 / 618 | 88.8% | 97.9% of 561 | ≥80% support |
| GO | GO:0043407 Biological Process | negative regulation of MAP kinase activity | 549 / 618 | 88.8% | 97.9% of 561 | ≥80% support |
| GO | GO:0046580 Biological Process | negative regulation of Ras protein signal transduction | 549 / 618 | 88.8% | 97.9% of 561 | ≥80% support |
| GO | GO:0048513 Biological Process | animal organ development | 549 / 618 | 88.8% | 97.9% of 561 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G234520 | CAB3998389.1 | sprouty homolog 2-like [Paramuricea clavata] | Q08E39 Protein sprouty homolog 2 OS=Bos taurus OX=9913 GN=SPRY2 PE= | JBrowse |
| Paragorgia papillata | Ppa0G267490 | CAB3978534.1 | sprouty homolog 2 [Paramuricea clavata] | Q9PTL2 Protein sprouty homolog 2 OS=Gallus gallus OX=9031 GN=SPRY2 | JBrowse |