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This orthogroup contains 567 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 567 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11680 | SERINE HYDROXYMETHYLTRANSFERASE | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| Pfam | PF00464 | SHMT — Serine hydroxymethyltransferase | 511 / 567 | 90.1% | 100.0% of 511 | ≥80% support |
| GO | GO:0004372 Molecular Function | glycine hydroxymethyltransferase activity | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0006565 Biological Process | L-serine catabolic process | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0006730 Biological Process | one-carbon metabolic process | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0019264 Biological Process | glycine biosynthetic process from serine | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0030170 Molecular Function | pyridoxal phosphate binding | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0046653 Biological Process | tetrahydrofolate metabolic process | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0046655 Biological Process | folic acid metabolic process | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0050897 Molecular Function | cobalt ion binding | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0070905 Molecular Function | serine binding | 512 / 567 | 90.3% | 100.0% of 512 | ≥80% support |
| GO | GO:0035999 Biological Process | tetrahydrofolate interconversion | 381 / 567 | 67.2% | 74.4% of 512 | ≥50% support |
| KEGG | K00600 | glyA, SHMT — Antifolate resistance | 387 / 567 | 68.3% | 99.0% of 391 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G150060 | XP_028395978.1 | serine hydroxymethyltransferase, mitochondrial-like [Dendronephthya gigantea] | P34897 Serine hydroxymethyltransferase, mitochondrial OS=Homo sapie | JBrowse |
| Paragorgia papillata | Ppa0G358280 | XP_028415862.1 | serine hydroxymethyltransferase, mitochondrial-like [Dendronephthya gigantea] | P34897 Serine hydroxymethyltransferase, mitochondrial OS=Homo sapie | JBrowse |
| Paragorgia papillata | Ppa0G358290 | XP_028415862.1 | serine hydroxymethyltransferase, mitochondrial-like [Dendronephthya gigantea] | P35623 Serine hydroxymethyltransferase, cytosolic OS=Ovis aries OX= | JBrowse |
