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This orthogroup contains 360 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 360 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11254 | HECT DOMAIN UBIQUITIN-PROTEIN LIGASE | 224 / 360 | 62.2% | 93.0% of 241 | ≥50% support |
| Pfam | PF06025 | DUF913 | 236 / 360 | 65.6% | 75.4% of 313 | ≥50% support |
| Pfam | PF14377 | UBM — Ubiquitin binding region | 220 / 360 | 61.1% | 70.3% of 313 | ≥50% support |
| Pfam | PF00632 | HECT | 219 / 360 | 60.8% | 70.0% of 313 | ≥50% support |
| Pfam | PF02825 | WWE | 214 / 360 | 59.4% | 68.4% of 313 | ≥50% support |
| Pfam | PF00627 | UBA | 211 / 360 | 58.6% | 67.4% of 313 | ≥50% support |
| Pfam | PF06012 | DUF908 | 203 / 360 | 56.4% | 64.9% of 313 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 230 / 360 | 63.9% | 85.8% of 268 | ≥50% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 224 / 360 | 62.2% | 83.6% of 268 | ≥50% support |
| GO | GO:0016567 Biological Process | protein ubiquitination | 224 / 360 | 62.2% | 83.6% of 268 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 224 / 360 | 62.2% | 83.6% of 268 | ≥50% support |
| GO | GO:0004842 Molecular Function | ubiquitin-protein transferase activity | 220 / 360 | 61.1% | 82.1% of 268 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 219 / 360 | 60.8% | 81.7% of 268 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G333860 | XP_028398427.1 | E3 ubiquitin-protein ligase HUWE1-like isoform X3 [Dendronephthya gigantea] | Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN | JBrowse |
