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This orthogroup contains 359 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 359 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13008 | MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS | 318 / 359 | 88.6% | 99.7% of 319 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 318 / 359 | 88.6% | 99.7% of 319 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 318 / 359 | 88.6% | 99.7% of 319 | ≥80% support |
| GO | GO:0032483 Biological Process | regulation of Rab protein signal transduction | 318 / 359 | 88.6% | 99.7% of 319 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 318 / 359 | 88.6% | 99.7% of 319 | ≥80% support |
| Pfam | PF02141 | DENN | 248 / 359 | 69.1% | 95.8% of 259 | ≥50% support |
| Pfam | PF03456 | uDENN | 218 / 359 | 60.7% | 84.2% of 259 | ≥50% support |
| KEGG | K26162 | MADD — Membrane trafficking | 199 / 359 | 55.4% | 97.6% of 204 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G269220 | XP_046860847.1 | MAP kinase-activating death domain protein-like isoform X1 [Xenia sp. Carnegie-2017] | Q80U28 MAP kinase-activating death domain protein OS=Mus musculus O | JBrowse |
