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This orthogroup contains 296 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 296 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11801 | SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION | 255 / 296 | 86.2% | 100.0% of 255 | ≥80% support |
| Pfam | PF21354 | STAT_linker — Signal transducer and activator of transcription, linker domain | 240 / 296 | 81.1% | 93.4% of 257 | ≥80% support |
| Pfam | PF02864 | STAT_bind — STAT protein, DNA binding domain | 239 / 296 | 80.7% | 93.0% of 257 | ≥80% support |
| GO | GO:0006355 Biological Process | regulation of DNA-templated transcription | 260 / 296 | 87.8% | 100.0% of 260 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 260 / 296 | 87.8% | 100.0% of 260 | ≥80% support |
| GO | GO:0007259 Biological Process | cell surface receptor signaling pathway via JAK-STAT | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0042127 Biological Process | regulation of cell population proliferation | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0006952 Biological Process | defense response | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0003700 Molecular Function | DNA-binding transcription factor activity | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 255 / 296 | 86.2% | 98.1% of 260 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 239 / 296 | 80.7% | 91.9% of 260 | ≥80% support |
| Pfam | PF00017 | SH2 | 214 / 296 | 72.3% | 83.3% of 257 | ≥50% support |
| Pfam | PF01017 | STAT_alpha — STAT protein, all-alpha domain | 214 / 296 | 72.3% | 83.3% of 257 | ≥50% support |
| Pfam | PF02865 | STAT_int — STAT protein, protein interaction domain | 160 / 296 | 54.1% | 62.3% of 257 | ≥50% support |
| KEGG | K11224 | STAT5B — Transcription factors | 194 / 296 | 65.5% | 98.0% of 198 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G387890 | XP_028415351.1 | signal transducer and activator of transcription 5A-like isoform X1 [Dendronephthya gigantea] | Q9TUZ1 Signal transducer and activator of transcription 5A OS=Sus s | JBrowse |
