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This orthogroup contains 289 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 289 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12415 | TYROSYL-DNA PHOSPHODIESTERASE 1 | 243 / 289 | 84.1% | 99.2% of 245 | ≥80% support |
| Pfam | PF06087 | Tyr-DNA_phospho — Tyrosyl-DNA phosphodiesterase | 249 / 289 | 86.2% | 97.7% of 255 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 249 / 289 | 86.2% | 99.6% of 250 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 249 / 289 | 86.2% | 99.6% of 250 | ≥80% support |
| GO | GO:0008081 Molecular Function | phosphoric diester hydrolase activity | 249 / 289 | 86.2% | 99.6% of 250 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 243 / 289 | 84.1% | 97.2% of 250 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 243 / 289 | 84.1% | 97.2% of 250 | ≥80% support |
| GO | GO:0017005 Molecular Function | 3'-tyrosyl-DNA phosphodiesterase activity | 243 / 289 | 84.1% | 97.2% of 250 | ≥80% support |
| Pfam | PF10283 | zf-CCHH — PBZ domain | 164 / 289 | 56.8% | 64.3% of 255 | ≥50% support |
| KEGG | K10862 | TDP1 — DNA repair and recombination proteins | 148 / 289 | 51.2% | 98.0% of 151 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G013680 | CAB3995701.1 | tyrosyl-DNA phosphodiesterase 1-like [Paramuricea clavata] | Q4G056 Tyrosyl-DNA phosphodiesterase 1 OS=Rattus norvegicus OX=1011 | JBrowse |