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This orthogroup contains 264 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 264 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45814 | HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 | 223 / 264 | 84.5% | 97.4% of 229 | ≥80% support |
| GO | GO:0042800 Molecular Function | histone H3K4 methyltransferase activity | 225 / 264 | 85.2% | 98.3% of 229 | ≥80% support |
| GO | GO:0051568 Biological Process | obsolete histone H3-K4 methylation | 224 / 264 | 84.9% | 97.8% of 229 | ≥80% support |
| GO | GO:0048188 Cellular Component | Set1C/COMPASS complex | 223 / 264 | 84.5% | 97.4% of 229 | ≥80% support |
| Pfam | PF00856 | SET | 192 / 264 | 72.7% | 84.6% of 227 | ≥50% support |
| Pfam | PF00076 | RRM_1 — RNA recognition motif | 182 / 264 | 68.9% | 80.2% of 227 | ≥50% support |
| Pfam | PF11764 | N-SET — COMPASS (Complex proteins associated with Set1p) component N | 165 / 264 | 62.5% | 72.7% of 227 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 192 / 264 | 72.7% | 83.8% of 229 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 186 / 264 | 70.5% | 81.2% of 229 | ≥50% support |
| GO | GO:0003723 Molecular Function | RNA binding | 183 / 264 | 69.3% | 79.9% of 229 | ≥50% support |
| KEGG | K11422 | SETD1, SET1 — Chromosome and associated proteins | 154 / 264 | 58.3% | 98.1% of 157 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G412340 | XP_028396807.1 | histone-lysine N-methyltransferase SETD1B-A-like [Dendronephthya gigantea] | Q9UPS6 Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens OX | JBrowse |
