← Back to the gene family browser
This orthogroup contains 252 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 252 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43290 | MEVALONATE KINASE | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| Pfam | PF00288 | GHMP_kinases_N — GHMP kinases N terminal domain | 206 / 252 | 81.8% | 92.4% of 223 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 228 / 252 | 90.5% | 100.0% of 228 | ≥80% support |
| GO | GO:0004496 Molecular Function | mevalonate kinase activity | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| GO | GO:0008299 Biological Process | isoprenoid biosynthetic process | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| GO | GO:0019287 Biological Process | isopentenyl diphosphate biosynthetic process, mevalonate pathway | 227 / 252 | 90.1% | 99.6% of 228 | ≥80% support |
| Pfam | PF08544 | GHMP_kinases_C — GHMP kinases C terminal | 198 / 252 | 78.6% | 88.8% of 223 | ≥50% support |
| GO | GO:0006695 Biological Process | cholesterol biosynthetic process | 173 / 252 | 68.7% | 75.9% of 228 | ≥50% support |
| KEGG | K00869 | MVK, mvaK1 — Peroxisome | 194 / 252 | 77.0% | 99.5% of 195 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G071960 | CAB3998576.1 | mevalonate kinase [Paramuricea clavata] | P17256 Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 | JBrowse |
| Paragorgia papillata | Ppa0G140360 | CAB3998576.1 | mevalonate kinase [Paramuricea clavata] | P17256 Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 | JBrowse |
| Paragorgia papillata | Ppa0G370390 | CAB3998576.1 | mevalonate kinase [Paramuricea clavata] | P17256 Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 | JBrowse |
| Paragorgia papillata | Ppa0G376930 | CAB3998576.1 | mevalonate kinase [Paramuricea clavata] | Q9R008 Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1 | JBrowse |
