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This orthogroup contains 241 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 241 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10507 | CDC45-RELATED PROTEIN | 210 / 241 | 87.1% | 98.1% of 214 | ≥80% support |
| Pfam | PF02724 | CDC45 | 211 / 241 | 87.6% | 98.6% of 214 | ≥80% support |
| GO | GO:0006270 Biological Process | DNA replication initiation | 212 / 241 | 88.0% | 98.6% of 215 | ≥80% support |
| GO | GO:0000727 Biological Process | double-strand break repair via break-induced replication | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| GO | GO:0003682 Molecular Function | chromatin binding | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| GO | GO:0003688 Molecular Function | DNA replication origin binding | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| GO | GO:0031261 Cellular Component | DNA replication preinitiation complex | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| GO | GO:1902977 Biological Process | mitotic DNA replication preinitiation complex assembly | 210 / 241 | 87.1% | 97.7% of 215 | ≥80% support |
| KEGG | K06628 | CDC45 — DNA replication proteins | 152 / 241 | 63.1% | 95.6% of 159 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G003200 | XP_028400506.1 | cell division control protein 45 homolog [Dendronephthya gigantea] | Q9YHZ6 Cell division control protein 45 homolog OS=Xenopus laevis O | JBrowse |
