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🧬 OG0005391

This orthogroup contains 237 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 86.5%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 237 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR12604KU AUTOANTIGEN DNA HELICASE205 / 23786.5%99.0%
of 207		≥80% support
PfamPF02735Ku193 / 23781.4%93.2%
of 207		≥80% support
PfamPF03730Ku_C — Ku70/Ku80 C-terminal arm193 / 23781.4%93.2%
of 207		≥80% support
GOGO:0006303
Biological Process		double-strand break repair via nonhomologous end joining208 / 23787.8%100.0%
of 208		≥80% support
GOGO:0000723
Biological Process		telomere maintenance207 / 23787.3%99.5%
of 208		≥80% support
GOGO:0042162
Molecular Function		telomeric DNA binding207 / 23787.3%99.5%
of 208		≥80% support
GOGO:0043564
Cellular Component		Ku70:Ku80 complex207 / 23787.3%99.5%
of 208		≥80% support
GOGO:0003690
Molecular Function		double-stranded DNA binding205 / 23786.5%98.6%
of 208		≥80% support
GOGO:0003677
Molecular Function		DNA binding202 / 23785.2%97.1%
of 208		≥80% support
GOGO:0003678
Molecular Function		DNA helicase activity193 / 23781.4%92.8%
of 208		≥80% support
GOGO:0005634
Cellular Component		nucleus191 / 23780.6%91.8%
of 208		≥80% support
GOGO:0003684
Molecular Function		damaged DNA binding190 / 23780.2%91.4%
of 208		≥80% support
PfamPF03731Ku_N — Ku70/Ku80 N-terminal alpha/beta domain185 / 23778.1%89.4%
of 207		≥50% support
KEGGK10884XRCC6, KU70, G22P1 — DNA repair and recombination proteins170 / 23771.7%97.7%
of 174		≥50% support
📊 Total members in OG0005391: 1 (filtered to PPAPI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Paragorgia papillataPpa0G270580XP_046862083.1X-ray repair cross-complementing protein 6-like [Xenia sp. Carnegie-2017]P12956
X-ray repair cross-complementing protein 6 OS=Homo sapiens O		JBrowse
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