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This orthogroup contains 234 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 234 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24355 | G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE | 201 / 234 | 85.9% | 99.5% of 202 | ≥80% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 189 / 234 | 80.8% | 94.0% of 201 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 202 / 234 | 86.3% | 100.0% of 202 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 202 / 234 | 86.3% | 100.0% of 202 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 201 / 234 | 85.9% | 99.5% of 202 | ≥80% support |
| GO | GO:0009966 Biological Process | regulation of signal transduction | 201 / 234 | 85.9% | 99.5% of 202 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 193 / 234 | 82.5% | 95.5% of 202 | ≥80% support |
| Pfam | PF00615 | RGS — Regulator of G protein signaling domain | 164 / 234 | 70.1% | 81.6% of 201 | ≥50% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 180 / 234 | 76.9% | 89.1% of 202 | ≥50% support |
| GO | GO:0004703 Molecular Function | G protein-coupled receptor kinase activity | 177 / 234 | 75.6% | 87.6% of 202 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 177 / 234 | 75.6% | 87.6% of 202 | ≥50% support |
| KEGG | K08291 | GRK4_5_6 — Protein kinases | 176 / 234 | 75.2% | 97.2% of 181 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G267930 | CAB3988926.1 | G -coupled receptor kinase 5-like [Paramuricea clavata] | P34947 G protein-coupled receptor kinase 5 OS=Homo sapiens OX=9606 | JBrowse |
