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This orthogroup contains 227 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 227 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23101 | RAB GDP/GTP EXCHANGE FACTOR | 173 / 227 | 76.2% | 97.2% of 178 | ≥50% support |
| Pfam | PF18151 | DUF5601 | 158 / 227 | 69.6% | 81.9% of 193 | ≥50% support |
| Pfam | PF02204 | VPS9 | 157 / 227 | 69.2% | 81.4% of 193 | ≥50% support |
| Pfam | PF00616 | RasGAP — GTPase-activator protein for Ras-like GTPase | 140 / 227 | 61.7% | 72.5% of 193 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 173 / 227 | 76.2% | 89.2% of 194 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 173 / 227 | 76.2% | 89.2% of 194 | ≥50% support |
| GO | GO:0016192 Biological Process | vesicle-mediated transport | 173 / 227 | 76.2% | 89.2% of 194 | ≥50% support |
| GO | GO:0030139 Cellular Component | endocytic vesicle | 173 / 227 | 76.2% | 89.2% of 194 | ≥50% support |
| GO | GO:0031267 Molecular Function | small GTPase binding | 173 / 227 | 76.2% | 89.2% of 194 | ≥50% support |
| GO | GO:0043087 Biological Process | regulation of GTPase activity | 151 / 227 | 66.5% | 77.8% of 194 | ≥50% support |
| KEGG | K27566 | GAPVD1 — Membrane trafficking | 126 / 227 | 55.5% | 97.7% of 129 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G326150 | XP_028410994.1 | GTPase-activating protein and VPS9 domain-containing protein 1-like isoform X2 [Dendronephthya gigantea] | Q6PAR5 GTPase-activating protein and VPS9 domain-containing protein | JBrowse |
