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This orthogroup contains 226 genes from 131 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 226 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10846 | SODIUM/POTASSIUM/CALCIUM EXCHANGER | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| Pfam | PF01699 | Na_Ca_ex — Sodium/calcium exchanger protein | 191 / 226 | 84.5% | 100.0% of 191 | ≥80% support |
| GO | GO:0005262 Molecular Function | calcium channel activity | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0006874 Biological Process | intracellular calcium ion homeostasis | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0008273 Molecular Function | calcium, potassium:sodium antiporter activity | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| GO | GO:0070588 Biological Process | calcium ion transmembrane transport | 191 / 226 | 84.5% | 99.5% of 192 | ≥80% support |
| KEGG | K13750 | SLC24A2, NCKX2 — Transporters | 113 / 226 | 50.0% | 98.3% of 115 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G367050 | CAB3999975.1 | sodium potassium calcium exchanger 2 isoform X3 [Paramuricea clavata] | Q9UI40 Sodium/potassium/calcium exchanger 2 OS=Homo sapiens OX=9606 | JBrowse |
