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This orthogroup contains 199 genes from 115 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 199 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46456 | DNA REPAIR PROTEIN RAD51 HOMOLOG 2 | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| Pfam | PF08423 | Rad51 | 179 / 199 | 90.0% | 100.0% of 179 | ≥80% support |
| GO | GO:0000400 Molecular Function | four-way junction DNA binding | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0005657 Cellular Component | replication fork | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0008094 Molecular Function | ATP-dependent activity, acting on DNA | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0033063 Cellular Component | Rad51B-Rad51C-Rad51D-XRCC2 complex | 184 / 199 | 92.5% | 100.0% of 184 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 179 / 199 | 90.0% | 97.3% of 184 | ≥80% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 179 / 199 | 90.0% | 97.3% of 184 | ≥80% support |
| KEGG | K10869 | RAD51L1, RAD51B — DNA repair and recombination proteins | 162 / 199 | 81.4% | 97.6% of 166 | ≥80% support |
| GO | GO:0016887 Molecular Function | ATP hydrolysis activity | 154 / 199 | 77.4% | 83.7% of 184 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Paragorgia papillata | Ppa0G207810 | XP_022779446.1 | DNA repair protein RAD51 homolog 2-like isoform X1 [Stylophora pistillata] | O15315 DNA repair protein RAD51 homolog 2 OS=Homo sapiens OX=9606 G | JBrowse |