Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 18 (filtered to PUMBR · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Palythoa umbrosac0150.g014.t1XP_020629888.1heart- and neural crest derivatives-expressed protein 2-like [Orbicella faveolata]P57102
Heart- and neural crest derivatives-expressed protein 2 OS=D
JBrowse
Palythoa umbrosac0150.g015.t1XP_001632876.2heart- and neural crest derivatives-expressed protein 2 [Nematostella vectensis]P61296
Heart- and neural crest derivatives-expressed protein 2 OS=H
JBrowse
Palythoa umbrosac0226.g007.t1XP_020617680.1T-cell acute lymphocytic leukemia protein 1-like [Orbicella faveolata]P12980
Protein lyl-1 OS=Homo sapiens OX=9606 GN=LYL1 PE=1 SV=3
JBrowse
Palythoa umbrosac0226.g008.t1XP_027041301.1protein atonal homolog 7-like [Pocillopora damicornis]O93507
T-cell acute lymphocytic leukemia protein 1 homolog OS=Danio
JBrowse
Palythoa umbrosac0226.g009.t1XP_031550006.1T-cell acute lymphocytic leukemia protein 1 homolog [Actinia tenebrosa]O73823
T-cell acute lymphocytic leukemia protein 1 OS=Xenopus laevi
JBrowse
Palythoa umbrosac0226.g010.t1XP_027041311.1T-cell acute lymphocytic leukemia protein 1 homolog [Pocillopora damicornis]Q16559
T-cell acute lymphocytic leukemia protein 2 OS=Homo sapiens
JBrowse
Palythoa umbrosac0733.g004.t1XP_020616252.1transcription factor 15-like [Orbicella faveolata]P48987
Protein atonal OS=Drosophila melanogaster OX=7227 GN=ato PE=
JBrowse
Palythoa umbrosac0733.g005.t1XP_015770453.1PREDICTED: twist-related protein-like [Acropora digitifera]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Palythoa umbrosac0733.g009.t1XP_020892182.1transcription factor 15 [Exaiptasia diaphana]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Palythoa umbrosac0737.g012.t1XP_020622947.1protein atonal homolog 8-like [Orbicella faveolata]D2CLZ9
Transcription factor atoh8 OS=Danio rerio OX=7955 GN=atoh8 P
JBrowse
Palythoa umbrosac0746.g010.t1XP_020892260.1basic helix-loop-helix transcription factor scleraxis [Exaiptasia diaphana]Q96RJ6
Fer3-like protein OS=Homo sapiens OX=9606 GN=FERD3L PE=1 SV=
JBrowse
Palythoa umbrosac0989.g008.t1XP_027048318.1protein atonal homolog 7-A-like [Pocillopora damicornis]–JBrowse
Palythoa umbrosac1212.g008.t1XP_020629353.1helix-loop-helix protein 2-like [Orbicella faveolata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Palythoa umbrosac1456.g002.t1CAH3157073.1unnamed protein product [Porites evermanni]Q20561
Helix-loop-helix protein 13 OS=Caenorhabditis elegans OX=623
JBrowse
Palythoa umbrosac1456.g003.t1XP_020917318.1pancreas transcription factor 1 subunit alpha [Exaiptasia diaphana]Q4ZHW1
Pancreas transcription factor 1 subunit alpha OS=Xenopus lae
JBrowse
Palythoa umbrosac1540.g002.t1XP_027048862.1achaete-scute homolog 1-like [Pocillopora damicornis]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Palythoa umbrosac1655.g001.t1XP_027048909.1achaete-scute homolog 3-like [Pocillopora damicornis]M0QWB7
Achaete-scute homolog 5 OS=Mus musculus OX=10090 GN=Ascl5 PE
JBrowse
Palythoa umbrosac1655.g002.t1CAH3162509.1unnamed protein product [Pocillopora meandrina]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
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