Gene Family

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Orthogroup

OG0000846

View gene tree Interactive tree, one tip per member sequence
Member genes
871
Species
130
Sequences
871
Best annotation support
83.4%
Downloads ⬇ Alignment (FASTA.gz) ⬇ Sequences (FASTA)

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 83.4% of the 871 members.

Support counts the member genes carrying the term. % of genes is that count over all 871 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11412MACROGLOBULIN / COMPLEMENT726 / 87183.4%99.5%
of 730		≥80% support
PfamPF07677A2M_recep — A-macroglobulin receptor binding domain480 / 87155.1%62.3%
of 771		≥50% support
PfamPF07678TED_complement — A-macroglobulin TED domain480 / 87155.1%62.3%
of 771		≥50% support
PfamPF07703A2M_BRD — Alpha-2-macroglobulin bait region domain454 / 87152.1%58.9%
of 771		≥50% support
PfamPF01759NTR453 / 87152.0%58.8%
of 771		≥50% support
PfamPF00207A2M — Alpha-2-macroglobulin family439 / 87150.4%56.9%
of 771		≥50% support
GOGO:0004866
Molecular Function		endopeptidase inhibitor activity512 / 87158.8%75.5%
of 678		≥50% support
GOGO:0005576
Cellular Component		extracellular region498 / 87157.2%73.5%
of 678		≥50% support
GOGO:0005615
Cellular Component		extracellular space481 / 87155.2%70.9%
of 678		≥50% support
GOGO:0005515
Molecular Function		protein binding457 / 87152.5%67.4%
of 678		≥50% support
📊 Total members in OG0000846: 2 (filtered to TMAIP · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Tripedalia maipoensisg11642.t1none–JBrowse
Tripedalia maipoensisg158.t1none–JBrowse
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