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This orthogroup contains 3,046 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,046 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10201 | MATRIX METALLOPROTEINASE | 2675 / 3,046 | 87.8% | 98.6% of 2,712 | ≥80% support |
| Pfam | PF00413 | Peptidase_M10 — Matrixin | 2571 / 3,046 | 84.4% | 93.7% of 2,743 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 2681 / 3,046 | 88.0% | 98.7% of 2,716 | ≥80% support |
| GO | GO:0030198 Biological Process | extracellular matrix organization | 2671 / 3,046 | 87.7% | 98.3% of 2,716 | ≥80% support |
| GO | GO:0030574 Biological Process | collagen catabolic process | 2671 / 3,046 | 87.7% | 98.3% of 2,716 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 2618 / 3,046 | 86.0% | 96.4% of 2,716 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 2600 / 3,046 | 85.4% | 95.7% of 2,716 | ≥80% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 2600 / 3,046 | 85.4% | 95.7% of 2,716 | ≥80% support |
| GO | GO:0031012 Cellular Component | extracellular matrix | 2596 / 3,046 | 85.2% | 95.6% of 2,716 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene10222.t1 | XP_020901217.1 | matrilysin isoform X2 [Exaiptasia diaphana] | Q9JHI0 Matrix metalloproteinase-19 OS=Mus musculus OX=10090 GN=Mmp1 | JBrowse |
| Actinoscyphia liui | gene10223.t1 | XP_031554167.1 | hatching enzyme-like [Actinia tenebrosa] | P22757 Hatching enzyme OS=Paracentrotus lividus OX=7656 PE=1 SV=1 | JBrowse |
| Actinoscyphia liui | gene10224.t1 | XP_031554167.1 | hatching enzyme-like [Actinia tenebrosa] | P09237 Matrilysin OS=Homo sapiens OX=9606 GN=MMP7 PE=1 SV=1 | JBrowse |
| Actinoscyphia liui | gene16880.t1 | XP_028516851.1 | matrix metalloproteinase-19 [Exaiptasia diaphana] | P22757 Hatching enzyme OS=Paracentrotus lividus OX=7656 PE=1 SV=1 | JBrowse |
| Actinoscyphia liui | gene17705.t1 | XP_020891960.1 | 72 kDa type IV collagenase [Exaiptasia diaphana] | O18927 Collagenase 3 OS=Equus caballus OX=9796 GN=MMP13 PE=2 SV=1 | JBrowse |
| Actinoscyphia liui | gene17706.t1 | XP_020891959.1 | LOW QUALITY PROTEIN: matrix metalloproteinase-17-like [Exaiptasia diaphana] | Q9NPA2 Matrix metalloproteinase-25 OS=Homo sapiens OX=9606 GN=MMP25 | JBrowse |
| Actinoscyphia liui | gene18031.t1 | XP_020899991.1 | matrix metalloproteinase-14 [Exaiptasia diaphana] | Q499S5 Stromelysin-3 OS=Rattus norvegicus OX=10116 GN=Mmp11 PE=1 SV | JBrowse |
| Actinoscyphia liui | gene26355.t1 | XP_020912518.1 | matrix metalloproteinase-9 [Exaiptasia diaphana] | Q9R0S2 Matrix metalloproteinase-24 OS=Mus musculus OX=10090 GN=Mmp2 | JBrowse |
| Actinoscyphia liui | gene26357.t1 | XP_020912518.1 | matrix metalloproteinase-9 [Exaiptasia diaphana] | Q9Y5R2 Matrix metalloproteinase-24 OS=Homo sapiens OX=9606 GN=MMP24 | JBrowse |
| Actinoscyphia liui | gene26358.t1 | XP_020912518.1 | matrix metalloproteinase-9 [Exaiptasia diaphana] | O04529 Metalloendoproteinase 2-MMP OS=Arabidopsis thaliana OX=3702 | JBrowse |
| Actinoscyphia liui | gene26362.t1 | XP_020898085.1 | matrilysin [Exaiptasia diaphana] | G5EBU3 Matrix metalloproteinase-C OS=Caenorhabditis elegans OX=6239 | JBrowse |
| Actinoscyphia liui | gene26367.t1 | XP_020916687.1 | macrophage metalloelastase [Exaiptasia diaphana] | O77656 Collagenase 3 OS=Bos taurus OX=9913 GN=MMP13 PE=2 SV=1 | JBrowse |
| Actinoscyphia liui | gene26876.t1 | XP_032230428.1 | matrilysin [Nematostella vectensis] | P09237 Matrilysin OS=Homo sapiens OX=9606 GN=MMP7 PE=1 SV=1 | JBrowse |