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This orthogroup contains 286 genes from 134 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 286 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24104 | E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED | 237 / 286 | 82.9% | 97.5% of 243 | ≥80% support |
| Pfam | PF01436 | NHL | 240 / 286 | 83.9% | 93.4% of 257 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 258 / 286 | 90.2% | 100.0% of 258 | ≥80% support |
| Pfam | PF01335 | DED — Death effector domain | 198 / 286 | 69.2% | 77.0% of 257 | ≥50% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 211 / 286 | 73.8% | 81.8% of 258 | ≥50% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 188 / 286 | 65.7% | 72.9% of 258 | ≥50% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 187 / 286 | 65.4% | 72.5% of 258 | ≥50% support |
| GO | GO:0043161 Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | 187 / 286 | 65.4% | 72.5% of 258 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Anthopleura xanthogrammica | ENSOJPP00000002850.1 | KXJ15821.1 | E3 ubiquitin-protein ligase TRIM71 [Exaiptasia diaphana] | – | JBrowse |
| Anthopleura xanthogrammica | ENSOJPP00000004362.1 | XP_031556784.1 | uncharacterized protein LOC116293490 [Actinia tenebrosa] | Q9JIG8 PRA1 family protein 2 OS=Mus musculus OX=10090 GN=Praf2 PE=1 | JBrowse |
