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This orthogroup contains 195 genes from 129 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 195 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10614 | INSULIN RECEPTOR SUBSTRATE | 151 / 195 | 77.4% | 98.1% of 154 | ≥50% support |
| Pfam | PF02174 | IRS | 139 / 195 | 71.3% | 92.1% of 151 | ≥50% support |
| Pfam | PF00169 | PH | 132 / 195 | 67.7% | 87.4% of 151 | ≥50% support |
| GO | GO:0005158 Molecular Function | insulin receptor binding | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0008286 Biological Process | insulin receptor signaling pathway | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0043548 Molecular Function | phosphatidylinositol 3-kinase binding | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Calvadosia cruxmelitensis | g430.t1 | XP_022799973.1 | insulin receptor substrate 1-like isoform X2 [Stylophora pistillata] | P35570 Insulin receptor substrate 1 OS=Rattus norvegicus OX=10116 G | JBrowse |
