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This orthogroup contains 195 genes from 129 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 195 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10614 | INSULIN RECEPTOR SUBSTRATE | 151 / 195 | 77.4% | 98.1% of 154 | ≥50% support |
| Pfam | PF02174 | IRS | 139 / 195 | 71.3% | 92.1% of 151 | ≥50% support |
| Pfam | PF00169 | PH | 132 / 195 | 67.7% | 87.4% of 151 | ≥50% support |
| GO | GO:0005158 Molecular Function | insulin receptor binding | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0008286 Biological Process | insulin receptor signaling pathway | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
| GO | GO:0043548 Molecular Function | phosphatidylinositol 3-kinase binding | 151 / 195 | 77.4% | 98.7% of 153 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora acuminata | aacu_s0184.g31.t1 | XP_015763438.1 | PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Alatina alata | Aala_g951.t1 | EDO49548.1 | predicted protein, partial [Nematostella vectensis] | A4IFM7 Myosin light chain kinase 2, skeletal/cardiac muscle OS=Bos | JBrowse |
| Aurelia aurita | scaffold187.g40.t1 | none | – | JBrowse | |
| Aurelia aurita | scaffold187.g40.t2 | none | – | JBrowse | |
| Aurelia aurita | scaffold187.g40.t3 | none | – | JBrowse | |
| Aurelia aurita complex sp. Pacific | scaffold229.g4.t1 | none | – | JBrowse | |
| Aurelia aurita complex sp. Pacific | scaffold229.g4.t2 | none | – | JBrowse | |
| Acropora austera | ENSKKQP00000042794.1 | XP_015763438.1 | PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora austera | ENSKKQP00000042805.1 | XP_015763438.1 | PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora austera | ENSKKQP00000042815.1 | XP_015763438.1 | PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora awi | aawi_s0295.g6.t1 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora cervicornis | KAK2548250.1 | XP_015763438.1 | PREDICTED: insulin receptor substrate 1-B-like [Acropora digitifera] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora cytherea | acyt_s0135.g43.t1 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora cytherea | acyt_s0135.g43.t2 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora digitifera | chr10Alt.g22715.t1 | none | – | JBrowse | |
| Acropora echinata | aech_s0003.g144.t1 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Actinia equina | EGACTEQ4350011897-PA | XP_031565638.1 | uncharacterized protein LOC116300822 [Actinia tenebrosa] | P84770 Insulin receptor substrate 1-B OS=Xenopus laevis OX=8355 GN= | JBrowse |
| Actinia equina | EGACTEQ4350016111-PA | none | – | JBrowse | |
| Acropora florida | aflo_s0258.g33.t1 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
| Acropora gemmifera | agem_s0050.g6.t1 | XP_029194807.2 | insulin receptor substrate 1-B-like [Acropora millepora] | Q6P4Y6 Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 G | JBrowse |
