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This orthogroup contains 194 genes from 131 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 194 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19290 | BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED | 170 / 194 | 87.6% | 97.7% of 174 | ≥80% support |
| Pfam | PF00010 | HLH — Helix-loop-helix DNA-binding domain | 173 / 194 | 89.2% | 99.4% of 174 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 174 / 194 | 89.7% | 100.0% of 174 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 172 / 194 | 88.7% | 98.9% of 174 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 133 / 194 | 68.6% | 76.4% of 174 | ≥50% support |
| GO | GO:0003700 Molecular Function | DNA-binding transcription factor activity | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0007423 Biological Process | sensory organ development | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0045944 Biological Process | positive regulation of transcription by RNA polymerase II | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0061564 Biological Process | axon development | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
| GO | GO:0070888 Molecular Function | E-box binding | 130 / 194 | 67.0% | 74.7% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Catostylus mosaicus | ENSSJYP00000006274.1 | XP_020896568.1 | neurogenic differentiation factor 1 [Exaiptasia diaphana] | O42202 Neurogenic differentiation factor 1 OS=Danio rerio OX=7955 G | JBrowse |
